Undesired toxicity is a major hindrance to drug discovery and largely responsible for high
attrition rates in early stages. This calls for new, reliable, and interpretable molecular …

Finding highly active molecular scaffold structures is always the key research content of new
pesticide discovery. In the research and development of new pesticides, the discovery of …

N, O-Containing heterocycles are incorporated in various approved pesticides and pesticide
candidates. The persistent challenge in modern crop protection is the continuous pursuit of …

The application of nano-catalysts in improving the ozonation removal efficiency for refractory
organic compounds has been extensively investigated. However, cost-effective nano …

Four new nitrogen-containing heterocyclic derivatives (acridine, quinoline, indole, pyridine)
were synthesized and their biological properties were evaluated. The compounds showed …

Isoxazoline is a novel structure with strong potential for controlling agricultural insect pests,
but its high toxicity to honeybees limits its development in agriculture. Herein, a series of N …

Quinolines have become essential to many drugs, including broad-spectrum antibiotics,
antivirus, antitubercular, and antimalarial agents. Owing to their importance in medicinal and …