Gene–environment interactions have important implications for elucidating the genetic basis
of complex diseases beyond the joint function of multiple genetic factors and their …

Objective Mental disorders are prevalent among the population and seriously endanger
people's working ability as well as their physical and mental health. This study employed …

Social and environmental stressors are crucial factors in child development. However, there
exists a multitude of measurable social and environmental factors—the effects of which may …

Pulmonary hypertension (PH) is a common disease that affects the normal functioning of the
human pulmonary arteries. The peripheral blood mononuclear cells (PMBCs) served as an …

Many methods have been developed to study nonparametric function-on-function
regression models. Nevertheless, there is a lack of model selection approach to the …

The quantile varying coefficient (VC) model can flexibly capture dynamical patterns of
regression coefficients. In addition, due to the quantile check loss function, it is robust …

Abstract Gene–environment (G× E) interactions have important implications to elucidate the
etiology of complex diseases beyond the main genetic and environmental effects. Outliers …

Lipid species are critical components of eukaryotic membranes. They play key roles in many
biological processes such as signal transduction, cell homeostasis, and energy storage …

Increasing evidence has shown that gene‐gene interactions have important effects in
biological processes of human diseases. Due to the high dimensionality of genetic …

In high-throughput genetics studies, an important aim is to identify gene–environment
interactions associated with the clinical outcomes. Recently, multiple marginal penalization …