Introduction The UK's current National Institute for Health and Care Excellence and the
American Psychiatric Association's depression guidelines state that withdrawal reactions …

Antidepressant drugs are prescribed to patients with depressive, anxiety disorders, and
other conditions. Evidence about antidepressant discontinuation syndrome (ADS) and …

Public Health England exists to protect and improve the nation's health and wellbeing, and
reduce health inequalities. We do this through world-leading science, research, knowledge …

Self-administration of very low doses of psychedelic drugs to improve mental health and
wellbeing and enhance cognitive function, known as microdosing, has received recent …

Background: Antidepressant withdrawal is experienced by about half of people who try to
reduce or come off their medication. It can be a debilitating, long lasting process. Many …

Background: Stopping antidepressants commonly causes withdrawal symptoms, which can
be severe and long-lasting. National Institute for Health and Care Excellence (NICE) …

Rationale The regular consumption of very small doses of psychedelic drugs (known as
microdosing) has been a source of growing media and community attention in recent years …

Background In recent years there has been growing media attention on microdosing
psychedelics (eg, LSD, psilocybin). This refers to people routinely taking small doses of …

Attempts to define selective serotonin reuptake inhibitor (SSRI) withdrawal with the term
'discontinuation syndrome'are not supported by evidence. Acknowledging that SSRI use can …

Introduction The incidence and severity of withdrawal effects when coming off
antidepressants (ADs) have recently received considerable attention. National guidelines on …