Piperacillin and tazobactam exhibit linear pharmacokinetics after multiple standard clinical doses
B Auclair, MP Ducharme - Antimicrobial agents and …, 1999 - Am Soc Microbiol
ABSTRACT A population pharmacokinetic (PK) analysis was conducted to determine if
piperacillin and tazobactam exhibited linear or nonlinear PKs and if incremental changes in …
piperacillin and tazobactam exhibited linear or nonlinear PKs and if incremental changes in …
Evaluating empiric treatment options for secondary peritonitis using pharmacodynamic profiling
KJ Eagye, JL Kuti, DP Nicolau - Surgical Infections, 2007 - liebertpub.com
Background: Selecting an appropriate agent for empiric antibiotic therapy for secondary
peritonitis is challenging. The pathogens responsible, aerobic gram-negative bacilli in …
peritonitis is challenging. The pathogens responsible, aerobic gram-negative bacilli in …
Carbapenems versus other beta-lactams in treating severe infections in intensive care: a systematic review of randomised controlled trials
SJ Edwards, MJ Clarke, S Wordsworth… - European Journal of …, 2008 - Springer
Carbapenems have not been comprehensively compared in clinical trials with fourth-
generation cephalosporins (4GC) and antipseudomonal penicillins (APP) in the treatment of …
generation cephalosporins (4GC) and antipseudomonal penicillins (APP) in the treatment of …
In Vitro Activities of Clindamycin, Imipenem, Metronidazole, and Piperacillin-Tazobactam against Susceptible and Resistant Isolates of Bacteroides fragilis Evaluated …
R Schaumann, M Funke, E Janssen… - Antimicrobial agents …, 2012 - Am Soc Microbiol
The aim of the present study was to investigate the activities of clindamycin, imipenem,
metronidazole, and piperacillin-tazobactam against 12 Bacteroides fragilis isolates (resistant …
metronidazole, and piperacillin-tazobactam against 12 Bacteroides fragilis isolates (resistant …
Ajuste de fármacos y nutrición en terapias de reemplazo renal continuo
J Echeverri, A Molano - Gaceta Médica de México, 2018 - medigraphic.com
Six to 23% of patients with acute kidney injury (AKI) in intensive care units (ICU) require
renal support. Continuous renal replacement therapies (CRRT) have become the modality …
renal support. Continuous renal replacement therapies (CRRT) have become the modality …
Pharmacodynamic modeling of β-lactam antibiotics for the empiric treatment of secondary peritonitis: a report from the OPTAMA program
S Kotapati, JL Kuti, DP Nicolau - Surgical Infections, 2005 - liebertpub.com
Background: In this report of the OPTAMA (Optimizing Pharmacodynamic Target Attainment
using the MYSTIC Antibiogram) program, we utilized Monte Carlo simulation to compare the …
using the MYSTIC Antibiogram) program, we utilized Monte Carlo simulation to compare the …
[PDF][PDF] Combating bacterial resistance to antimicrobials in severe septic ICU patients: importance of meropenem, piperacillin serum monitoring as a dose adjustment …
SRCJ Santos, TV Camargo, CG Messiano… - Pharmacy & …, 2023 - repositorio.usp.br
USP affiliated authors: SANTOS, SILVIA REGINA CAVANI JORGE-FCF; SILVA JUNIOR,
JOÃO MANOEL DA-FM; GOMEZ, DAVID DE SOUZA-FM; KUPA, LEONARD DE VINCI …
JOÃO MANOEL DA-FM; GOMEZ, DAVID DE SOUZA-FM; KUPA, LEONARD DE VINCI …
[PDF][PDF] Application of beta-lactam therapeutic drug monitoring in clinical practice using HPLC
T Urakami, Y Aoki, M Fukuoka, H Magarifuchi… - J Bioanal …, 2011 - researchmap.jp
In beta-lactam therapy, investigation of the pharmacokinetic-pharmacodynamic (PK-PD)
relationship has provided surrogate makers to predict clinical outcome. This study was …
relationship has provided surrogate makers to predict clinical outcome. This study was …
Pharmacokinetic/pharmacodynamic modeling to predict in vivo effectiveness of various dosing regimens of piperacillin/tazobactam and piperacillin monotherapy …
CR Frei, DS Burgess - Clinical therapeutics, 2008 - Elsevier
Objective: This study compared the pharmacokinetic/pharmacodynamic (PK/PD) properties
of piperacillin/tazobactam (PTZ) combination treatment with those of piperacillin (PIP) …
of piperacillin/tazobactam (PTZ) combination treatment with those of piperacillin (PIP) …
Influence of culture site-specific MIC distributions on the pharmacokinetic and pharmacodynamic properties of piperacillin/tazobactam and piperacillin: A data analysis
CR Frei, SL Hampton, DS Burgess - Clinical therapeutics, 2006 - Elsevier
BACKGROUND:: Investigators who perform pharmacokinetic/pharmacodynamic (PK-PD)
modeling with Monte Carlo simulation have historically not stratified microbiological data by …
modeling with Monte Carlo simulation have historically not stratified microbiological data by …