Inflammatory bowel disease (IBD) is a chronic disorder associated with the inflammation in
the digestive tract. The exact cause of IBD is unknown; nevertheless, in IBD, the …

Nuclear factor of κB (NF-κB) is a sequence-specific transcription factor that is known to be
involved in the inflammatory and innate immune responses. Although the importance of NF …

NF-κB in defense and disease ing lymphocyte activation (8). The chemotherapeutic agent
etoposide also increases NF-κB levels and thereby induces A1/Bfl-1, which prevents …

Ribosomal protein S6 (RPS6) is a component of the 40S small ribosomal subunit and
participates in the control of mRNA translation. Additionally, phospho (p)-RPS6 has been …

Nuclear factor-κB (NF-κB)/Rel transcription factors have been suspected since their
discovery to play a pivotal role in chronic and acute inflammatory diseases. It now seems …

Abstract Resveratrol (trans-3, 4′, 5-trihydroxystilbene), a polyphenolic phytoalexin found in
grapes, fruits, and root extracts of the weed Polygonum cuspidatum, exhibits anti …

Nuclear factor kappa B (NF-κB) transcription factors regulate several important physiological
processes, including inflammation and immune responses, cell growth, apoptosis, and the …

Background & Aims: The transcription factor nuclear factor–κB (NF-κB) plays a central role in
regulating immune and inflammatory responses. Because butyrate deficiency has been …

5-aminosalicylic acid (5-ASA) is an antiinflammatory drug widely used in the treatment of
inflammatory bowel diseases. It is known to inhibit the production of cytokines and …

The process of tumorigenesis requires cellular transformation, hyperproliferation, invasion,
angiogenesis, and metastasis. Several genes that mediate these processes are regulated …