We have reached single-visit testing, diagnosis, and treatment for hepatitis C infection, now what?
Introduction Progress toward hepatitis C virus (HCV) elimination is impeded by low testing
and treatment due to the current diagnostic pathway requiring multiple visits leading to loss …
and treatment due to the current diagnostic pathway requiring multiple visits leading to loss …
Whole genome sequencing of clinical strains of Mycobacterium tuberculosis from Mumbai, India: a potential tool for determining drug-resistance and strain lineage
Amplification of drug resistance in Mycobacterium tuberculosis (M. tb) and its transmission
are significant barriers in controlling tuberculosis (TB) globally. Diagnostic inaccuracies and …
are significant barriers in controlling tuberculosis (TB) globally. Diagnostic inaccuracies and …
The value proposition for pathologists: a population health approach
BS Ducatman, AM Ducatman… - Academic …, 2020 - journals.sagepub.com
The transition to a value-based payment system offers pathologists the opportunity to play
an increased role in population health by improving outcomes and safety as well as …
an increased role in population health by improving outcomes and safety as well as …
[HTML][HTML] Comparison of GeneXpert and line probe assay for detection of Mycobacterium tuberculosis and rifampicin-mono resistance at the National Tuberculosis …
SA Aricha, L Kingwara, NW Mwirigi, L Chaba… - BMC infectious …, 2019 - Springer
Background The dual challenge of low diagnostic sensitivity of microscopy test and technical
challenge of performing a TB culture test poses a problem for case detection and initiation of …
challenge of performing a TB culture test poses a problem for case detection and initiation of …
Using molecular testing and whole-genome sequencing for tuberculosis diagnosis in a low-burden setting: a cost-effectiveness analysis using transmission-dynamic …
T Mugwagwa, I Abubakar, PJ White - Thorax, 2021 - thorax.bmj.com
Background Despite progress in TB control in low-burden countries like England and Wales,
there are still diagnostic delays. Molecular testing and/or whole-genome sequencing (WGS) …
there are still diagnostic delays. Molecular testing and/or whole-genome sequencing (WGS) …
Validation of novel Mycobacterium tuberculosis isoniazid resistance mutations not detectable by common molecular tests
JL Kandler, AD Mercante, TL Dalton… - Antimicrobial agents …, 2018 - Am Soc Microbiol
Resistance to the first-line antituberculosis (TB) drug isoniazid (INH) is widespread, and the
mechanism of resistance is unknown in approximately 15% of INH-resistant (INH-R) strains …
mechanism of resistance is unknown in approximately 15% of INH-resistant (INH-R) strains …
Multicenter Study of the Accuracy of the BD MAX Multidrug-resistant Tuberculosis Assay for Detection of Mycobacterium tuberculosis Complex and Mutations …
M Shah, S Paradis, J Betz, N Beylis… - Clinical Infectious …, 2020 - academic.oup.com
Background Tuberculosis (TB) control is hindered by absence of rapid tests to identify
Mycobacterium tuberculosis (MTB) and detect isoniazid (INH) and rifampin (RIF) resistance …
Mycobacterium tuberculosis (MTB) and detect isoniazid (INH) and rifampin (RIF) resistance …
What will it take to eliminate drug-resistant tuberculosis?
Drug-resistant tuberculosis (DR-TB) is challenging to diagnose, treat, and prevent, but this
situation is slowly changing. If the world is to drastically reduce the incidence of DR-TB, we …
situation is slowly changing. If the world is to drastically reduce the incidence of DR-TB, we …
[HTML][HTML] “I Do Feel Like a Scientist at Times”: A Qualitative Study of the Acceptability of Molecular Point-Of-Care Testing for Chlamydia and Gonorrhoea to Primary …
Background Point-of-care tests for chlamydia (CT) and gonorrhoea (NG) could increase the
uptake and timeliness of testing and treatment, contribute to improved disease control and …
uptake and timeliness of testing and treatment, contribute to improved disease control and …
Evolution of phenotypic and molecular drug susceptibility testing
DM Cirillo, P Miotto, E Tortoli - … tuberculosis complex: its role in biology …, 2017 - Springer
Abstract Drug Resistant Tuberculosis (DRTB) is an emerging problem world-wide. In order
to control the disease and decrease the number of cases overtime a prompt diagnosis …
to control the disease and decrease the number of cases overtime a prompt diagnosis …