Cytokines in inflammatory disease
This review aims to briefly discuss a short list of a broad variety of inflammatory cytokines.
Numerous studies have implicated that inflammatory cytokines exert important effects with …
Numerous studies have implicated that inflammatory cytokines exert important effects with …
Targeting cell death: pyroptosis, ferroptosis, apoptosis and necroptosis in osteoarthritis
J Yang, S Hu, Y Bian, J Yao, D Wang, X Liu… - Frontiers in cell and …, 2022 - frontiersin.org
New research has shown that the development of osteoarthritis (OA) is regulated by different
mechanisms of cell death and types of cytokines. Therefore, elucidating the mechanism of …
mechanisms of cell death and types of cytokines. Therefore, elucidating the mechanism of …
Melatonin suppresses ferroptosis induced by high glucose via activation of the Nrf2/HO‐1 signaling pathway in type 2 diabetic osteoporosis
H Ma, X Wang, W Zhang, H Li, W Zhao… - Oxidative medicine …, 2020 - Wiley Online Library
Ferroptosis is recently identified, an iron‐and reactive oxygen species‐(ROS‐) dependent
form of regulated cell death. This study was designed to determine the existence of …
form of regulated cell death. This study was designed to determine the existence of …
Oxidative stress and inflammation in osteoporosis: molecular mechanisms involved and the relationship with microRNAs
T Iantomasi, C Romagnoli, G Palmini, S Donati… - International journal of …, 2023 - mdpi.com
Osteoporosis is characterized by the alteration of bone homeostasis due to an imbalance
between osteoclastic bone resorption and osteoblastic bone formation. Estrogen deficiency …
between osteoclastic bone resorption and osteoblastic bone formation. Estrogen deficiency …
Inflammasomes in alveolar bone loss
Y Li, J Ling, Q Jiang - Frontiers in immunology, 2021 - frontiersin.org
Bone remodeling is tightly controlled by osteoclast-mediated bone resorption and osteoblast-
mediated bone formation. Fine tuning of the osteoclast–osteoblast balance results in strict …
mediated bone formation. Fine tuning of the osteoclast–osteoblast balance results in strict …
Melatonin and inflammation—Story of a double‐edged blade
R Hardeland - Journal of pineal research, 2018 - Wiley Online Library
Melatonin is an immune modulator that displays both pro‐and anti‐inflammatory properties.
Proinflammatory actions, which are well documented by many studies in isolated cells or …
Proinflammatory actions, which are well documented by many studies in isolated cells or …
[HTML][HTML] Cell death regulation: a new way for natural products to treat osteoporosis
Z Li, D Li, R Chen, S Gao, Z Xu, N Li - Pharmacological Research, 2023 - Elsevier
Osteoporosis is a common metabolic bone disease that results from the imbalance of
homeostasis within the bone. Intra-bone homeostasis is dependent on a precise dynamic …
homeostasis within the bone. Intra-bone homeostasis is dependent on a precise dynamic …
[HTML][HTML] Is melatonin the cornucopia of the 21st century?
N Ferlazzo, G Andolina, A Cannata, MG Costanzo… - Antioxidants, 2020 - mdpi.com
Melatonin, an indoleamine hormone produced and secreted at night by pinealocytes and
extra-pineal cells, plays an important role in timing circadian rhythms (24-h internal clock) …
extra-pineal cells, plays an important role in timing circadian rhythms (24-h internal clock) …
NLRP3 inflammasome: a new target for prevention and control of osteoporosis?
N Jiang, J An, K Yang, J Liu, C Guan, C Ma… - Frontiers in …, 2021 - frontiersin.org
Osteoporosis is a systemic bone metabolism disease that often causes complications, such
as fractures, and increases the risk of death. The nucleotide-binding oligomerization domain …
as fractures, and increases the risk of death. The nucleotide-binding oligomerization domain …
NLRP3 regulates alveolar bone loss in ligature‐induced periodontitis by promoting osteoclastic differentiation
Y Chen, Q Yang, C Lv, Y Chen, W Zhao, W Li… - Cell …, 2021 - Wiley Online Library
Objectives NLRP3 inflammasome is a critical part of the innate immune system and plays an
important role in a variety of inflammatory diseases. However, the effects of NLRP3 …
important role in a variety of inflammatory diseases. However, the effects of NLRP3 …