Gastric cancer remains a major cause of cancer-related mortality worldwide. The temporal
trends for this malignancy, however, are dynamic, and reports from the past decade indicate …

Gastric cancer is a major source of global cancer mortality with limited treatment options and
poor patient survival. As our molecular understanding of gastric cancer improves, we are …

Objective Tumour heterogeneity represents a major obstacle to accurate diagnosis and
treatment in gastric adenocarcinoma (GA). Here, we report a systematic transcriptional atlas …

Invasive gastric carcinoma is preceded by a cascade of precancerous lesions. The first
recognized histologic change is active chronic inflammation, which may persist as such: non …

Background & Aims Almost all gastric cancers are adenocarcinomas, which have
considerable heterogeneity among patients. We sought to identify subtypes of gastric …

Gastric cancer, 1 of the 5 most common causes of cancer death, is associated with a 5-year
overall survival rate less than 30%. A minority of cancers occurs as part of syndromic …

Despite the global prevalence of gastric disease, there are few adequate models in which to
study the fundus epithelium of the human stomach. We differentiated human pluripotent …

Gastric colonization with Helicobacter pylori induces diverse human pathological conditions,
including superficial gastritis, peptic ulcer disease, mucosa-associated lymphoid tissue …

Western countries are seeing a constant decline in the incidence of Helicobacter pylori-
associated gastritis, coupled with a rising epidemiological and clinical impact of autoimmune …

Gastric intestinal metaplasia is a precancerous change of the mucosa of the stomach with
intestinal epithelium, and is associated with an increased risk of dysplasia and cancer. The …