Alternative splicing and related RNA binding proteins in human health and disease
Y Tao, Q Zhang, H Wang, X Yang, H Mu - Signal Transduction and …, 2024 - nature.com
Alternative splicing (AS) serves as a pivotal mechanism in transcriptional regulation,
engendering transcript diversity, and modifications in protein structure and functionality …
engendering transcript diversity, and modifications in protein structure and functionality …
[HTML][HTML] Bioinspired cellular membrane-derived vesicles for mRNA delivery
X Xu, L Xu, J Wang, C Wen, J Xia, Y Zhang, Y Liang - Theranostics, 2024 - ncbi.nlm.nih.gov
The rapid advancement of mRNA as vaccines and therapeutic agents in the biomedical field
has sparked hope in the fight against untreatable diseases. Successful clinical application of …
has sparked hope in the fight against untreatable diseases. Successful clinical application of …
Circular RNA circATP9A promotes non-small cell lung cancer progression by interacting with HuR and by promoting extracellular vesicles-mediated macrophage M2 …
Y Yao, C Chen, J Wang, H Xuan, X Chen, Z Li… - Journal of Experimental …, 2023 - Springer
Background CircRNA is recognized for its significant regulatory function across various
cancers. However, its regulatory role in non-small cell lung cancer (NSCLC) is still largely …
cancers. However, its regulatory role in non-small cell lung cancer (NSCLC) is still largely …
Hepatitis B virus RNAs co-opt ELAVL1 for stabilization and CRM1-dependent nuclear export
Y Zheng, M Wang, J Yin, Y Duan, C Wu, Z Xu… - Plos …, 2024 - journals.plos.org
Hepatitis B virus (HBV) chronically infects 296 million people worldwide, posing a major
global health threat. Export of HBV RNAs from the nucleus to the cytoplasm is indispensable …
global health threat. Export of HBV RNAs from the nucleus to the cytoplasm is indispensable …
Circular RNA RHBDD1 regulates tumorigenicity and ferroptosis in colorectal cancer by mediating the ELAVL1/SCD mRNA interaction
F Long, C Zhong, Q Long, K Zhu, J Wang, Y Yu… - Cancer Gene …, 2024 - nature.com
Circular RNAs (circRNAs) are covalently closed noncoding RNA molecules that play
multiple roles in tumorigenesis and metastasis. Ferroptosis is an iron-dependent, regulated …
multiple roles in tumorigenesis and metastasis. Ferroptosis is an iron-dependent, regulated …
The role of ADAR1 through and beyond its editing activity in cancer
Y Jiao, Y Xu, C Liu, R Miao, C Liu, Y Wang… - Cell Communication and …, 2024 - Springer
Abstract Adenosine-to-inosine (A-to-I) editing of RNA, catalyzed by adenosine deaminase
acting on RNA (ADAR) enzymes, is a prevalent RNA modification in mammals. It has been …
acting on RNA (ADAR) enzymes, is a prevalent RNA modification in mammals. It has been …
Regulatory mechanism of circular RNA involvement in osteoarthritis
Y Zhang, L Liu, K Liu, M Wang, X Su, J Wang - Frontiers in Surgery, 2023 - frontiersin.org
Osteoarthritis (OA) causes joint pain, stiffness, and dysfunction in middle-aged and older
adults; however, its pathogenesis remains unclear. Circular RNAs (circRNAs) are …
adults; however, its pathogenesis remains unclear. Circular RNAs (circRNAs) are …
LncRNA EBLN3P Facilitates Osteosarcoma Metastasis by Enhancing Annexin A3 mRNA Stability and Recruiting HuR
S Wang, X Zeng, P Gui, S Xu, Z Li, D Chen - Annals of Surgical Oncology, 2023 - Springer
Background Osteosarcoma (OS) represents a common type of bone cancer. Long non-
coding RNAs (LncRNAs) have shown their potential in therapeutic modalities for OS. This …
coding RNAs (LncRNAs) have shown their potential in therapeutic modalities for OS. This …
MicroRNAs miR-16 and miR-519 control meningioma cell proliferation via overlapping transcriptomic programs shared with the RNA-binding protein HuR
S Hergalant, JM Casse, A Oussalah… - Frontiers in …, 2023 - frontiersin.org
Introduction Meningiomas are the most common type of primary central nervous system
tumors. In about 80% cases, these tumors are benign and grow very slowly, but the …
tumors. In about 80% cases, these tumors are benign and grow very slowly, but the …
Emerging roles of RNA binding proteins in intervertebral disc degeneration and osteoarthritis
W Li, XH Li, Y Gao, CJ Xiong, ZZ Tang - Orthopaedic Surgery, 2023 - Wiley Online Library
The etiology of intervertebral disc degeneration (IDD) and osteoarthritis (OA) is complex and
multifactorial. Both predisposing genes and environmental factors are involved in the …
multifactorial. Both predisposing genes and environmental factors are involved in the …