Spinal cord injury (SCI) is a devastating neurological condition prevalent worldwide. Where
the pathological mechanisms underlying SCI are concerned, we can distinguish between …

Neuroinflammation has a significant impact on different pathologies, such as stroke or spinal
cord injury, intervening in their pathophysiology: expansion, progression, and resolution …

Numerous studies have shown that neuroinflammation is involved in the process of
neuronal damage in neurodegenerative diseases such as Parkinson's disease (PD), for …

Neuropathic pain is one of the most debilitating forms of chronic pain, resulting from an
injury or disease of the somatosensory nervous system, which induces abnormal painful …

Background Microglial activation in the spinal trigeminal nucleus (STN) plays a crucial role
in the development of trigeminal neuralgia (TN). The involvement of adenosine …

This study examined the effects of turmeric bioactive compounds, curcumin C3
complex®(CUR) and bisdemethoxycurcumin (BDMC), on mechanical hypersensitivity and …

Objective The inflammatory response is acknowledged as a crucial pathological aspect of
spinal cord injury (SCI). Tetramethylpyrazine (TMP) has been demonstrated to possess …

Traumatic central nervous system (CNS) injuries, including spinal cord injury and traumatic
brain injury, are challenging enemies of human health. Microglia, the main component of the …

N-docosahexaenoylethanolamine, or synaptamide, is an endogenous metabolite of
docosahexaenoic acid that is known for synaptogenic and neurogenic effects. In our …

This study investigated the antinociceptive potential of cannabidiol (CBD) in male and
female Wistar rats. The assessment and analysis included tail withdrawal to thermal …