The physics, biophysics and technology of photodynamic therapy

BC Wilson, MS Patterson - Physics in Medicine & Biology, 2008 - iopscience.iop.org
Photodynamic therapy (PDT) uses light-activated drugs to treat diseases ranging from
cancer to age-related macular degeneration and antibiotic-resistant infections. This paper …

Recent advances in diffuse optical imaging

AP Gibson, JC Hebden, SR Arridge - Physics in medicine & …, 2005 - iopscience.iop.org
We review the current state-of-the-art of diffuse optical imaging, which is an emerging
technique for functional imaging of biological tissue. It involves generating images using …

Tutorial on diffuse light transport

SL Jacques, BW Pogue - Journal of biomedical optics, 2008 - spiedigitallibrary.org
A tutorial introduction to diffuse light transport is presented. The basic analytic equations of
time-resolved, steady-state and modulated light transport are introduced. The perturbation …

Lighting up tumors with receptor-specific optical molecular probes

S Achilefu - Technology in cancer research & treatment, 2004 - journals.sagepub.com
Accurate and rapid detection of tumors is of great importance for interrogating the molecular
basis of cancer pathogenesis, preventing the onset of complications, and implementing a …

Fast segmentation and high-quality three-dimensional volume mesh creation from medical images for diffuse optical tomography

M Jermyn, H Ghadyani… - … of biomedical optics, 2013 - spiedigitallibrary.org
Multimodal approaches that combine near-infrared (NIR) and conventional imaging
modalities have been shown to improve optical parameter estimation dramatically and thus …

Three‐dimensional diffuse optical tomography in the parallel plane transmission geometry: Evaluation of a hybrid frequency domain/continuous wave clinical system …

JP Culver, R Choe, MJ Holboke, L Zubkov… - Medical …, 2003 - Wiley Online Library
Three‐dimensional diffuse optical tomography (DOT) of breast requires large data sets for
even modest resolution (1 cm). We present a hybrid DOT system that combines a limited …

Multiwavelength three-dimensional near-infrared tomography of the breast: initial simulation, phantom, and clinical results

H Dehghani, BW Pogue, SP Poplack, KD Paulsen - Applied Optics, 2003 - opg.optica.org
Three-dimensional (3D), multiwavelength near-infrared tomography has the potential to
provide new physiological information about biological tissue function and pathological …

Near-infrared (NIR) tomography breast image reconstruction with a priori structural information from MRI: algorithm development for reconstructing heterogeneities

BA Brooksby, H Dehghani, BW Pogue… - IEEE Journal of …, 2003 - ieeexplore.ieee.org
A combined magnetic resonance and near-infrared (MRI-NIR) imaging modality can
potentially yield high resolution maps of optical properties from noninvasive simultaneous …

Characterization of hemoglobin, water, and NIR scattering in breast tissue: analysis of intersubject variability and menstrual cycle changes

BW Pogue, S Jiang, H Dehghani… - … of biomedical optics, 2004 - spiedigitallibrary.org
Near-infrared imaging was used to quantify typical values of hemoglobin concentration,
oxygen saturation, water fraction, scattering power, and scattering amplitude within the …

Three-dimensional optical tomography: resolution in small-object imaging

H Dehghani, BW Pogue, J Shudong, B Brooksby… - Applied …, 2003 - opg.optica.org
Near-infrared (NIR) optical tomography can provide estimates of the internal distribution of
optical absorption and transport scattering from boundary measurements of light …