Platelet transfusion: and update on challenges and outcomes
P Solves Alcaina - Journal of blood medicine, 2020 - Taylor & Francis
Platelet transfusion is a common practice in onco-hematologic patients for preventing or
treating hemorrhages. Platelet concentrates can be transfused with therapeutic or …
treating hemorrhages. Platelet concentrates can be transfused with therapeutic or …
Human leukocyte antigen alloimmunization and alloimmune platelet refractoriness
A Saris, K Pavenski - Transfusion Medicine Reviews, 2020 - Elsevier
Despite significant advancements in the production of platelet products, storage, and
transfusion, transfusion refractoriness remains a significant clinical problem, affecting up to …
transfusion, transfusion refractoriness remains a significant clinical problem, affecting up to …
Challenges and advances in managing thrombocytopenic cancer patients
A Leader, L Hofstetter, G Spectre - Journal of clinical medicine, 2021 - mdpi.com
Cancer patients have varying incidence, depth and duration of thrombocytopenia. The
mainstay of managing severe chemotherapy-induced thrombocytopenia (CIT) in cancer is …
mainstay of managing severe chemotherapy-induced thrombocytopenia (CIT) in cancer is …
Exploration of risk factors of platelet transfusion refractoriness and its impact on the prognosis of hematopoietic stem cell transplantation: a retrospective study of …
X Song, J Qi, X Li, M Zhou, J He, T Chu, Y Han - Platelets, 2023 - Taylor & Francis
Platelet transfusion refractoriness (PTR) is an intractable issue in hematological patients,
which increases bleeding risks and hospitalization costs to a great extent. We reviewed 108 …
which increases bleeding risks and hospitalization costs to a great extent. We reviewed 108 …
A meta-analysis of risk factors associated with platelet transfusion refractoriness
X Song, J Qi, K Fang, X Li, Y Han - International Journal of Hematology, 2023 - Springer
Background Platelet transfusion refractoriness (PTR) remains an intractable issue in clinical
practice, and is common in hematological patients. At present, it is believed that both …
practice, and is common in hematological patients. At present, it is believed that both …
Relieving DYRK1A repression of MKL1 confers an adult-like phenotype to human infantile megakaryocytes
KE Elagib, A Brock, CM Clementelli… - The Journal of …, 2022 - Am Soc Clin Investig
Infantile (fetal and neonatal) megakaryocytes (Mks) have a distinct phenotype consisting of
hyperproliferation, limited morphogenesis, and low platelet production capacity. These …
hyperproliferation, limited morphogenesis, and low platelet production capacity. These …
HLA‐selected platelets for platelet refractory patients with HLA antibodies: a single‐center experience
C Karlström, T Linjama, G Edgren, J Lauronen… - …, 2019 - Wiley Online Library
BACKGROUND Platelet refractoriness due to HLA immunization represents a problem in
transfusion management of thrombocytopenic hematology patients. Refractory patients can …
transfusion management of thrombocytopenic hematology patients. Refractory patients can …
Cost estimate of platelet transfusion in the United States for patients with chronic liver disease and associated thrombocytopenia undergoing elective procedures
CL Barnett, D Mladsi, M Vredenburg… - Journal of Medical …, 2018 - Taylor & Francis
Aims: This study aimed to estimate the cost of platelet transfusion in patients with chronic
liver disease (CLD)-associated thrombocytopenia undergoing an elective procedure in the …
liver disease (CLD)-associated thrombocytopenia undergoing an elective procedure in the …
A systematic literature review on the use of platelet transfusions in patients with thrombocytopenia
Objective: Investigate globally, current treatment patterns, benefit-risk assessments,
humanistic, societal and economic burden of platelet transfusion (PT). Methods: Publications …
humanistic, societal and economic burden of platelet transfusion (PT). Methods: Publications …
Platelet component transfusion and alloimmunization: where do we stand?
P Moncharmont - Transfusion Clinique et Biologique, 2018 - Elsevier
Platelet transfusion in patients, particularly in onco-haematology, is frequent and can
become chronic in some cases. Post-transfusion alloimmunization is often seen, in practice …
become chronic in some cases. Post-transfusion alloimmunization is often seen, in practice …