Senescence and SASP Are Potential Therapeutic Targets for Ischemic Stroke
Aging is a known co-morbidity of ischemic stroke with its risk and severity increasing every
year past 55+. While many of the current stroke therapies have shown success in reducing …
year past 55+. While many of the current stroke therapies have shown success in reducing …
Perspective from single‐cell sequencing: Is inflammation in acute ischemic stroke beneficial or detrimental?
X Deng, Z Hu, S Zhou, Y Wu, M Fu… - CNS Neuroscience …, 2024 - Wiley Online Library
Background Acute ischemic stroke (AIS) is a common cerebrovascular event associated with
high incidence, disability, and poor prognosis. Studies have shown that various cell types …
high incidence, disability, and poor prognosis. Studies have shown that various cell types …
[HTML][HTML] Microglial TNFR2 signaling regulates the inflammatory response after CNS injury in a sex-specific fashion
S Raffaele, E Thougaard, CCH Laursen, H Gao… - Brain, behavior, and …, 2024 - Elsevier
Microglia, the resident immune cells of the central nervous system (CNS), play a major role
in damage progression and tissue remodeling after acute CNS injury, including ischemic …
in damage progression and tissue remodeling after acute CNS injury, including ischemic …