Highlights of the drug-induced liver injury literature for 2021
SM Woo, DM Alhaqqan, DT Gildea… - Expert Review of …, 2022 - Taylor & Francis
ABSTRACT Introduction In 2021, over 3,000 articles on Drug-Induced Liver Injury (DILI)
were published, nearly doubling the annual number compared to 2011. This review selected …
were published, nearly doubling the annual number compared to 2011. This review selected …
Simultaneous detection of mitochondrial viscosity and peroxynitrite in livers from subjects with drug-induced fatty liver disease using a novel fluorescent probe
L Niu, Q Cao, T Zhang, Y Zhang, T Liang, J Wang - Talanta, 2023 - Elsevier
Drug-induced fatty liver disease (DIFLD) is a basic clinicopathological example of drug-
induced liver injury (DILI). Some drugs can inhibit β-oxidation in hepatocyte mitochondria …
induced liver injury (DILI). Some drugs can inhibit β-oxidation in hepatocyte mitochondria …
Permeabilized cryopreserved human hepatocytes as an exogenous metabolic system in a novel metabolism-dependent cytotoxicity assay for the evaluation of …
H Wei, AP Li - Drug Metabolism and Disposition, 2022 - ASPET
We report here a novel in vitro experimental system, the metabolism-dependent cytotoxicity
assay (MDCA), for the definition of the roles of hepatic drug metabolism in toxicity. MDCA …
assay (MDCA), for the definition of the roles of hepatic drug metabolism in toxicity. MDCA …
Development of a Scoring System to Differentiate Amiodarone-Induced Liver Injury From Alcoholic Steatohepatitis
IA González, LD Fuller, X Zhang… - American journal of …, 2022 - academic.oup.com
Objectives Amiodarone-induced liver injury (AILI) is histopathologically similar to alcoholic
steatohepatitis (ASH). We sought to elucidate their histologic differences and develop a …
steatohepatitis (ASH). We sought to elucidate their histologic differences and develop a …
[PDF][PDF] Permeabilized cryopreserved human hepatocytes as an exogenous metabolic system in a novel
H Wei, AP Li - researchgate.net
We report here a novel in vitro experimental system, the metabolism-dependent cytotoxicity
assay (MDCA), for the definition of the roles of hepatic drug metabolism in toxicity. MDCA …
assay (MDCA), for the definition of the roles of hepatic drug metabolism in toxicity. MDCA …