Obesity in children and adolescents: epidemiology, causes, assessment, and management

H Jebeile, AS Kelly, G O'Malley… - The lancet Diabetes & …, 2022 - thelancet.com
This Review describes current knowledge on the epidemiology and causes of child and
adolescent obesity, considerations for assessment, and current management approaches …

[HTML][HTML] The energy balance model of obesity: beyond calories in, calories out

KD Hall, IS Farooqi, JM Friedman, S Klein… - The American journal of …, 2022 - Elsevier
ABSTRACT A recent Perspective article described the “carbohydrate-insulin model (CIM)” of
obesity, asserting that it “better reflects knowledge on the biology of weight control” as …

[HTML][HTML] The Asian Pacific Association for the Study of the Liver clinical practice guidelines for the diagnosis and management of metabolic associated fatty liver …

M Eslam, SK Sarin, VWS Wong, JG Fan… - Hepatology …, 2020 - Springer
Metabolic associated fatty liver disease (MAFLD) is the principal worldwide cause of liver
disease and affects nearly a quarter of the global population. The objective of this work was …

[HTML][HTML] The carbohydrate-insulin model: a physiological perspective on the obesity pandemic

DS Ludwig, LJ Aronne, A Astrup, R de Cabo… - The American journal of …, 2021 - Elsevier
According to a commonly held view, the obesity pandemic is caused by overconsumption of
modern, highly palatable, energy-dense processed foods, exacerbated by a sedentary …

[HTML][HTML] GDF15 promotes weight loss by enhancing energy expenditure in muscle

D Wang, LK Townsend, GJ DesOrmeaux, SM Frangos… - Nature, 2023 - nature.com
Caloric restriction that promotes weight loss is an effective strategy for treating non-alcoholic
fatty liver disease and improving insulin sensitivity in people with type 2 diabetes. Despite its …

The science of obesity management: an endocrine society scientific statement

GA Bray, WE Heisel, A Afshin, MD Jensen… - Endocrine …, 2018 - academic.oup.com
The prevalence of obesity, measured by body mass index, has risen to unacceptable levels
in both men and women in the United States and worldwide with resultant hazardous health …

Obesity: a chronic relapsing progressive disease process. A position statement of the World Obesity Federation

GA Bray, KK Kim, JPH Wilding… - Obesity …, 2017 - Wiley Online Library
This paper considers the argument for obesity as a chronic relapsing disease process.
Obesity is viewed from an epidemiological model, with an agent affecting the host and …

Obesity: pathophysiology and management

KM Gadde, CK Martin, HR Berthoud… - Journal of the American …, 2018 - jacc.org
Obesity continues to be among the top health concerns across the globe. Despite our failure
to contain the high prevalence of obesity, we now have a better understanding of its …

Maintenance of lost weight and long-term management of obesity

KD Hall, S Kahan - Medical Clinics, 2018 - medical.theclinics.com
Robert is a 47-year-old patient who initially weighed 120 kilograms. He lost 40 kilograms 3
years ago by carefully following your guidance to decrease his caloric intake to 1500 …

[HTML][HTML] Diets and drugs for weight loss and health in obesity–An update

J Aaseth, S Ellefsen, U Alehagen, TM Sundfør… - Biomedicine & …, 2021 - Elsevier
Numerous combinations of diets and pharmacological agents, including lifestyle changes,
have been launched to treat obesity. There are still ambiguities regarding the efficacies of …