Background The emergence of carbapenemase producing bacteria, especially New Delhi
metallo-β-lactamase (NDM-1) and its variants, worldwide, has raised amajor public health …

Microorganisms are highly resistant to the antibiotics that are commonly used and thus are
becoming serious public health problem. There is an urgent need for new approaches to …

Background Increasing antimicrobial resistance among pathogens that cause complicated
intraabdominal infections (cIAIs) supports the development of new antimicrobials …

The aging process is accompanied by the onset of disease and a general decline in
wellness. Insights into the aging process have revealed a number of cellular hallmarks of …

Nosocomial infections with Acinetobacter baumannii are a global problem in intensive care
units with high mortality rates. Increasing resistance to first-and second-line antibiotics has …

There is an increasing interest in revisiting plants for drug discovery, proving scientifically
their role as remedies. The aim of this review was to give an overview of the …

The antibiotic pipeline continues to diminish and the majority of the public remains unaware
of this critical situation. The cause of the decline of antibiotic development is multifactorial …

Since the advent of penicillin, humans have known about and explored the phenomenon of
bacterial inhibition via antibiotics. However, with changes in the global environment and the …

Antimicrobial resistance (AMR) is a well-recognized global threat. The World Health
Organization (WHO) issued a report ranking the critical types of bacterial resistance that …

Background Quantifying antibiotic use is an essential element of antibiotic stewardship since
it allows comparison between different settings and time windows, and measurement of the …