Progestogens used in postmenopausal hormone therapy: differences in their pharmacological properties, intracellular actions, and clinical effects

FZ Stanczyk, JP Hapgood, S Winer… - Endocrine …, 2013 - academic.oup.com
The safety of progestogens as a class has come under increased scrutiny after the
publication of data from the Women's Health Initiative trial, particularly with respect to breast …

All progestins are not created equal

FZ Stanczyk - Steroids, 2003 - Elsevier
A variety of progestins are available for therapeutic use. It is convenient to classify them into
those related in chemical structure to progesterone or testosterone. Progestins related to …

Bioavailability of orally administered sex steroids used in oral contraception and hormone replacement therapy

K Fotherby - Contraception, 1996 - Elsevier
The concept of bioavailability is discussed with particular references to the sex steroids.
Problems encountered in the measurement of bioavailability of these steroids and the …

Pharmacokinetics and potency of progestins used for hormone replacement therapy and contraception

FZ Stanczyk - Reviews in Endocrine and Metabolic Disorders, 2002 - Springer
Progestins are compounds that exhibit progestational activity. The most widely recognized
progestational activity is transformation of proliferative to secretory endometrium in estrogen …

[图书][B] Combined estrogen-progestogen contraceptives and combined estrogen-progestogen menopausal therapy

IARC Working Group on the Evaluation of … - 2007 - books.google.com
This ninety-first volume of IARC Monographscontains evaluations of the carcinogenic
hazard to humans of combined estrogen-progestogen contraceptives and combined …

Reported jealousy differs as a function of menstrual cycle stage and contraceptive pill use: A within-subjects investigation

KD Cobey, AP Buunk, SC Roberts, C Klipping… - Evolution and Human …, 2012 - Elsevier
Previous research suggests that female jealousy is sensitive to hormonal variation and,
more specifically, potentially moderated by estrogen levels. Here, we tracked self-reported …

Oral contraceptives and individual variability of circulating levels of ethinyl estradiol and progestins

JW Goldzieher, FZ Stanczyk - Contraception, 2008 - Elsevier
When the 19-norsteroids norethynodrel and norethindrone (norethisterone)—which differ
only by the position of a single double bond—were synthesized (independently and almost …

Effects of felbamate on the pharmacokinetics of a low‐dose combination oral contraceptive

V Saano, P Glue, CR Banfield… - Clinical …, 1995 - Wiley Online Library
The effects of felbamate on the pharmacokinetics of a low‐dose combination oral
contraceptive containing 30 μg ethinyl estradiol and 75 μg gestodene were assessed in a …

Gestodene: a review of its pharmacology, potency and tolerability in combined contraceptive preparations

FZ Stanczyk, DF Archer - Contraception, 2014 - Elsevier
Combined progestin–estrogen pills are an established and reliable contraceptive option
used by women worldwide. Combined oral contraceptives (COCs) containing the progestins …

Predicting the oral bioavailability of 19-nortestosterone progestins in vivo from their metabolic stability in human liver microsomal preparations in vitro

W Kuhnz, H Gieschen - Drug metabolism and disposition, 1998 - ASPET
It was the aim of this study to investigate whether assessment of the metabolic stability of
selected progestins of the 19-nortestosterone type in human microsomal liver preparations …