A Practical Toolkit for the Detection, Isolation, Quantification, and Characterization of Siderophores and Metallophores in Microorganisms

AFR Gomes, E Sousa, DISP Resende - ACS omega, 2024 - ACS Publications
Siderophores are well-recognized low-molecular-weight compounds produced by
numerous microorganisms to acquire iron from the surrounding environments. These …

Microbial siderophores in metal detoxification and therapeutics: recent prospective and applications

R Sharma, R Bhardwaj, V Gautam, SK Kohli… - Plant microbiome: stress …, 2018 - Springer
Siderophores are small molecular weight metal scavengers which are released by plants,
plant growth-promoting bacterial strains and fungi into the rhizosphere. These molecules …

Both metal-chelating and free radical-scavenging synthetic pentapeptides as efficient inhibitors of reactive oxygen species generation

G Csire, L Canabady-Rochelle, MC Averlant-Petit… - Metallomics, 2020 - academic.oup.com
Reactive oxygen species (ROS) are major sources of oxidative stress playing prominent
roles in the development of several pathologies including cardiovascular and …

Toxicity of the iron siderophore mycobactin J in mouse macrophages: Evidence for a hypoxia response

CF McQueen, JT Groves - Journal of Inorganic Biochemistry, 2022 - Elsevier
Mycobacterium tuberculosis, the causative agent of tuberculosis, is an obligate intracellular
pathogen that lives within the phagosome of macrophages. Here we demonstrate that the …

Strategic design and development of a siderophore mimic: Pioneering anticancer therapy via ROS generation and ferroptosis

A Panwar, A Lye, D Musib, A Upadhyay… - Dalton …, 2024 - pubs.rsc.org
We designed a tris-catecholate-based siderophore mimic, H6-T-CATL, to selectively chelate
iron (III) from mitochondrial cytochromes and other iron-containing proteins within cellular …

Quantitative proteomic analysis of iron-regulated outer membrane proteins in Aeromonas hydrophila as potential vaccine candidates

Y Wang, H Chen, Z Guo, L Sun, Y Fu, T Li, W Lin… - Fish & shellfish …, 2017 - Elsevier
The iron-regulated outer membrane protein (OMP) of Aeromonas hydrophila is an effective
vaccine candidate, but its intrinsic functional components are largely unknown. In this study …

Acetyl-CoA-Mediated Post-Biosynthetic Modification of Desferrioxamine B Generates N- and N-O-Acetylated Isomers Controlled by a pH Switch

KP Nolan, J Font, A Sresutharsan… - ACS Chemical …, 2022 - ACS Publications
Biosynthesis of the hydroxamic acid siderophore desferrioxamine D1 (DFOD1, 6), which is
the N-acetylated analogue of desferrioxamine B (DFOB, 5), has been delineated. Enzyme …

Plant growth promoting rhizobacteria in phytoremediation of environmental contaminants: challenges and future prospects

J Prakash - Bioremediation for Environmental Sustainability, 2021 - Elsevier
Phytoremediation is a technique in which plants can degrade, stabilize, and/or remove the
environmental contaminants (organic and inorganic pollutants) from polluted soil. This …

Enterobactin on a bead: parallel, solid phase siderophore synthesis reveals structure–activity relationships for iron uptake in bacteria

MB Nodwell, R Britton - ACS Infectious Diseases, 2020 - ACS Publications
A solid-phase platform for the precise and sequential synthesis of enterobactin analogues is
described. This chemistry unites the power of solid-phase peptide synthesis with the unique …

[HTML][HTML] Nobachelins, new siderophores from Nocardiopsis baichengensis protecting Caenorhabditis elegans from Pseudomonas aeruginosa infection

H Zhao, Y Ren, F Xie, H Dai, H Liu, C Fu… - Synthetic and Systems …, 2023 - Elsevier
The biosynthetic potential of actinobacteria to produce novel natural products is still
regarded as immense. In this paper, we correlated a cryptic biosynthetic gene cluster to …