Aging is a risk factor for heart failure, which is a leading cause of death world-wide. Elderly
patients are more likely than young patients to experience a myocardial infarction (MI) and …

Heart disease causing cardiac cell death due to ischemia–reperfusion injury is a major
cause of morbidity and mortality in the United States. Coronary heart disease and …

Background—Cardiac interstitial fibrosis is a major cause of the deteriorated performance of
the heart in patients with chronic myocardial infarction. MicroRNAs (miRs) have recently …

Background—Postinfarction cardiac repair is regulated through timely activation and
repression of inflammatory pathways, followed by transition to fibrous tissue deposition and …

Aims In patients with ischaemic heart failure (HF), myocardial dysfunction often progresses.
Elevated levels of soluble ST2 (sST2) are associated with a poor prognosis, but an …

Following myocardial infarction (MI), the heart undergoes a pathological process known as
remodeling, which in many instances results in cardiac dysfunction and ultimately heart …

The first experience with endoventricular circular patch plasty (EVCPP) was reported in
1984 as a surgical method to rebuild left ventricular (LV) geometry made more spheric after …

The IL-33/ST2L signaling pathway, involved in the pathophysiological processes of several
diseases, mainly plays anti-inflammatory and anti-fibrotic effects. Soluble Suppression of …

BACKGROUND AND PURPOSE Interstitial fibrosis plays a causal role in the development of
heart failure after chronic myocardial infarction (MI), and anti‐fibrotic therapy represents a …

Background and Aims Myocardial infarction (MI) is accompanied by increased collagen
deposition, cell necrosis and angiogenesis in cardiac tissue, which results in reduced …