Ferroptosis, a unique modality of cell death with mechanistic and morphological differences
from other cell death modes, plays a pivotal role in regulating tumorigenesis and offers a …

Preclinical models of human disease provide powerful tools for therapeutic discovery but
have limitations. This problem is especially apparent in the field of acute kidney injury (AKI) …

Background Acute kidney injury (AKI) is the most common and serious complication of
sepsis, accompanied by high mortality and disease burden. The early prediction of AKI is …

Although sepsis and acute kidney injury (AKI) have a bidirectional interplay, the
pathophysiological mechanisms between AKI and sepsis are not clarified and worthy of a …

Our earlier studies indicated that reactive oxygen species (ROS) were involved in
lipopolysaccharide (LPS)-induced acute kidney injury (AKI). The present study aimed to …

Sepsis has evolved as an enormous health issue amongst critically ill patients. It is a major
risk factor that results in multiple organ failure and shock. Acute kidney injury (AKI) is one of …

Sepsis is a heterogenous and highly complex clinical syndrome, which is caused by
infectious or noninfectious factors. Acute kidney injury (AKI) is one of the most common and …

Liensinine is mainly derived from alkaloids extracted and isolated from lotus seeds
(Nelumbo nucifera Gaertn). It possesses anti-inflammatory, and antioxidant, according to …

Sepsis is a clinical syndrome resulting from infection followed by inflammation and is one of
the significant causes of mortality worldwide. The underlying reason is the host's …

Background Acute kidney injury (AKI) is a frequent consequence of sepsis and has been
linked to poor prognosis. In critically ill patients, the ratio of neutrophils to lymphocytes and …