[HTML][HTML] Recent advances in nanomedicines for photodynamic therapy (PDT)-driven cancer immunotherapy

B Ji, M Wei, B Yang - Theranostics, 2022 - ncbi.nlm.nih.gov
Cancer immunotherapy has made tremendous clinical progress in advanced-stage
malignancies. However, patients with various tumors exhibit a low response rate to …

Emerging connectivity of programmed cell death pathways and its physiological implications

S Bedoui, MJ Herold, A Strasser - Nature reviews Molecular cell biology, 2020 - nature.com
The removal of functionally dispensable, infected or potentially neoplastic cells is driven by
programmed cell death (PCD) pathways, highlighting their important roles in homeostasis …

Microenvironment‐responsive prodrug‐induced pyroptosis boosts cancer immunotherapy

Y Xiao, T Zhang, X Ma, QC Yang, LL Yang… - Advanced …, 2021 - Wiley Online Library
The absence of tumor antigens leads to a low response rate, which represents a major
challenge in immune checkpoint blockade (ICB) therapy. Pyroptosis, which releases tumor …

Synthetic phenolic antioxidants: Metabolism, hazards and mechanism of action

X Xu, A Liu, S Hu, I Ares, MR Martínez-Larrañaga… - Food Chemistry, 2021 - Elsevier
Synthetic phenolic antioxidants can interact with peroxides produced by food. This paper
reviews correlation between BHA, BHT and TBHQ metabolism and harms they cause and …

Mechanism of ferroptosis and its role in type 2 diabetes mellitus

W Sha, F Hu, Y Xi, Y Chu, S Bu - Journal of diabetes research, 2021 - Wiley Online Library
Ferroptosis is a novel form of nonapoptotic regulated cell death (RCD). It features iron‐
dependent lipid peroxide accumulation accompanied by inadequate redox enzymes …

Apoptosis and apoptotic body: disease message and therapeutic target potentials

X Xu, Y Lai, ZC Hua - Bioscience reports, 2019 - portlandpress.com
Apoptosis is widely known as programmed cell death eliciting no inflammatory responses.
The intricacy of apoptosis has been a focus of an array of researches, accumulating a wealth …

[HTML][HTML] Targeting apoptotic caspases in cancer

A Boice, L Bouchier-Hayes - … et Biophysica Acta (BBA)-Molecular Cell …, 2020 - Elsevier
Members of the caspase family of proteases play essential roles in the initiation and
execution of apoptosis. These caspases are divided into two groups: the initiator caspases …

[PDF][PDF] Glutaminolysis and transferrin regulate ferroptosis

M Gao, P Monian, N Quadri, R Ramasamy, X Jiang - Molecular cell, 2015 - cell.com
Ferroptosis has emerged as a new form of regulated necrosis that is implicated in various
human diseases. However, the mechanisms of ferroptosis are not well defined. This study …

miR-137 regulates ferroptosis by targeting glutamine transporter SLC1A5 in melanoma

M Luo, L Wu, K Zhang, H Wang, T Zhang… - Cell Death & …, 2018 - nature.com
Ferroptosis is a regulated form of cell death driven by small molecules or conditions that
induce lipid-based reactive oxygen species (ROS) accumulation. This form of iron …

Major apoptotic mechanisms and genes involved in apoptosis

Y Kiraz, A Adan, M Kartal Yandim, Y Baran - Tumor Biology, 2016 - Springer
As much as the cellular viability is important for the living organisms, the elimination of
unnecessary or damaged cells has the opposite necessity for the maintenance of …