Three-dimensional protein structure is directly correlated with its function and its
determination is critical to understanding biological processes and addressing human …

Highlights•AlphaFold models have rigid protein structures.•Advanced deep algorithms fed
relevant data can accurately predict structures.•Algorithmic advances can harness …

We present the results for CAPRI Round 54, the 5th joint CASP‐CAPRI protein assembly
prediction challenge. The Round offered 37 targets, including 14 homodimers, 3 homo …

Abstract Salt-inducible kinase 2 (SIK2) has been recognized as a potential target for anti-
inflammation and anti-cancer therapy. In this paper, based on the binding pose of the …

Chagas disease is the most important protozoan infection in the Americas, and constitutes a
significant public health concern throughout the world. Development of new medications …

The release of ChatGPT has sparked quite a bit of interest about creativity in the context of
artificial intelligence (AI), with theorizing and empirical research asking questions about the …

Recent years have seen a sharp increase in the development of deep learning and artificial
intelligence-based molecular informatics. There has been a growing interest in applying …

Economic valorization of lignocellulose is paramount to realizing a true circular bioeconomy;
however, this requires the development of systems and processes to expand the repertoire …

Beyond their function as structural barriers, plant cell walls are essential elements for the
adaptation of plants to environmental conditions. Cell walls are dynamic structures whose …

Protein folding is a complex physicochemical process whereby a polymer of amino acids
samples numerous conformations in its unfolded state before settling on an essentially …