Meta-analysis of five genome-wide association studies identifies multiple new loci associated with testicular germ cell tumor
Abstract The international Testicular Cancer Consortium (TECAC) combined five published
genome-wide association studies of testicular germ cell tumor (TGCT; 3,558 cases and …
genome-wide association studies of testicular germ cell tumor (TGCT; 3,558 cases and …
Rate of pathogenic germline variants in patients with lung cancer
S Sorscher, J LoPiccolo, B Heald, E Chen… - JCO Precision …, 2023 - ascopubs.org
PURPOSE Germline genetic testing (GGT) is now recommended for all patients diagnosed
with ovarian or pancreatic cancer and for a large proportion of patients based solely on a …
with ovarian or pancreatic cancer and for a large proportion of patients based solely on a …
[HTML][HTML] Identification of 22 susceptibility loci associated with testicular germ cell tumors
Testicular germ cell tumors (TGCT) are the most common tumor in young white men and
have a high heritability. In this study, the international Testicular Cancer Consortium …
have a high heritability. In this study, the international Testicular Cancer Consortium …
Targeting monocytes/macrophages in fibrosis and cancer diseases: Therapeutic approaches
E Conte - Pharmacology & Therapeutics, 2022 - Elsevier
Over almost 140 years since their identification, the knowledge about macrophages has
unbelievably evolved. The'big eaters' from being thought of as simple phagocytic cells have …
unbelievably evolved. The'big eaters' from being thought of as simple phagocytic cells have …
[HTML][HTML] Disease heritability inferred from familial relationships reported in medical records
Heritability is essential for understanding the biological causes of disease but requires
laborious patient recruitment and phenotype ascertainment. Electronic health records …
laborious patient recruitment and phenotype ascertainment. Electronic health records …
[HTML][HTML] Burden of prostate cancer in China, 1990–2019: findings from the 2019 global burden of disease study
F Wang, C Wang, H Xia, Y Lin, D Zhang… - Frontiers in …, 2022 - frontiersin.org
Our study is the first to illustrate the age and geographic distribution differences in the
epidemiology of prostate cancer from 1990 to 2019 in China. Prostate cancer (PC) is a …
epidemiology of prostate cancer from 1990 to 2019 in China. Prostate cancer (PC) is a …
Prostate cancer screening in African American men: a review of the evidence
KH Kensler, R Johnson, F Morley… - JNCI: Journal of the …, 2024 - academic.oup.com
Background Prostate cancer is the most diagnosed cancer in African American men, yet
prostate cancer screening regimens in this group are poorly guided by existing evidence …
prostate cancer screening regimens in this group are poorly guided by existing evidence …
[HTML][HTML] Cross-ancestry GWAS meta-analysis identifies six breast cancer loci in African and European ancestry women
Our study describes breast cancer risk loci using a cross-ancestry GWAS approach. We first
identify variants that are associated with breast cancer at P< 0.05 from African ancestry …
identify variants that are associated with breast cancer at P< 0.05 from African ancestry …
[HTML][HTML] Genetic susceptibility to endometrial cancer: Risk factors and clinical management
T Dörk, P Hillemanns, C Tempfer, J Breu, MC Fleisch - Cancers, 2020 - mdpi.com
Endometrial cancer (EC) is the most common cancer affecting the female reproductive
organs in higher-income states. Apart from reproductive factors and excess weight, genetic …
organs in higher-income states. Apart from reproductive factors and excess weight, genetic …
Diagnosis and management of anxiety disorders
P Giacobbe, A Flint - CONTINUUM: Lifelong Learning in …, 2018 - journals.lww.com
PURPOSE OF REVIEW This article provides a synopsis of the current understanding of the
pathophysiology of anxiety disorders, the biological and environmental risk factors that …
pathophysiology of anxiety disorders, the biological and environmental risk factors that …