Regulated cell death (RCD), also well-known as programmed cell death (PCD), refers to the
form of cell death that can be regulated by a variety of biomacromolecules, which is …

Reactive oxygen species (ROS) are essential for cellular signaling and response to stress.
The level of ROS and the type of ROS determine the ability of cells to undergo cell death …

Over the past decade, the Nomenclature Committee on Cell Death (NCCD) has formulated
guidelines for the definition and interpretation of cell death from morphological, biochemical …

Ferroptosis is an iron-dependent form of regulated necrosis. It is implicated in various
human diseases, including ischemic organ damage and cancer. Here, we report the crucial …

Ischemic disorders, such as myocardial infarction, stroke, and peripheral vascular disease,
are the most common causes of debilitating disease and death in westernized cultures. The …

Ferroptosis has emerged as a new form of regulated necrosis that is implicated in various
human diseases. However, the mechanisms of ferroptosis are not well defined. This study …

Necroptosis is a form of regulated cell death that critically depends on receptor-interacting
serine-threonine kinase 3 (RIPK3) and mixed lineage kinase domain-like (MLKL) and …

Cell death is the irreversible stop of life. It is also the basic physiological process of all
organisms which involved in the embryonic development, organ maintenance and …

This review encompasses the most important advances in liver functions and hepatotoxicity
and analyzes which mechanisms can be studied in vitro. In a complex architecture of nested …

Tumor necrosis factor (TNF) is the prototypic pro-inflammatory cytokine. It is central to host
defense and inflammatory responses but under certain circumstances also triggers cell …