Cullin-RING E3 ubiquitin ligase 4 (CRL4) plays an essential role in cell cycle progression.
Recent efforts using high throughput screening and follow up hit-to-lead studies have led to …

Long noncoding RNAs (lncRNAs) are important players in laryngeal squamous cell
carcinoma (LSCC). However, the function of the long noncoding RNA small nucleolar RNA …

Abstract MiR-181a-2 plays a major role in cell proliferation both positively and negatively
depending on tissue type by targeting several regulators 3′ UTR regions. We have …

目的探讨左卡尼汀对氟尿嘧啶(5-fluorouracil, 5-Fu) 抑制人胃腺癌MGC803
细胞增殖作用的影响. 方法将MGC803 细胞分为阴性对照组, 5-Fu 组, 左卡尼汀和5-Fu …

Limited therapeutic options exist for patients with or at risk of developing metastatic disease.
YAP and TAZ are transcriptional co-activators that often drive TEAD-mediated transcription …

This thesis reports on an investigation into the molecular biology and metabolism of two
species: Cycasfugax, a critically endangered cycad; and Celastrus hindsii, a traditional …

FİSETİN İLE KOMBİNE EDİLMİŞ KEMOTERAPİ İLAÇLARININ KOLOREKTAL KANSER
HÜCRELERİNE ETKİSİ ÜZERİNE ÇALIŞMALAR Page 1 TÜRKİYE CUMHURİYETİ MARMARA …

The small non-coding RNAs termed microRNAs can induce post-transcriptional silencing of
genes critical to the pathogenesis of multiple cancers. Such microRNAs are deregulated and …

Background: Nucleolar and spindle associated protein (NUSAP1) is involved in tumor
initiation, progression and metastasis. However, there are limited studies regarding the role …

Gastric cancer (GC) is the fifth most prevalent malignancy and the third leading cause of
cancer-related death worldwide, with 1,000,000 new cases and 750,000 deaths annually [1] …