Microneedle array systems for long-acting drug delivery

LK Vora, K Moffatt, IA Tekko, AJ Paredes… - European Journal of …, 2021 - Elsevier
The development of microneedles (MNs) assisted drug delivery technologies have been
highly active for more than two decades. The minimally invasive and self-administered MN …

The role of stiffness in cell reprogramming: a potential role for biomaterials in inducing tissue regeneration

M d'Angelo, E Benedetti, MG Tupone, M Catanesi… - Cells, 2019 - mdpi.com
The mechanotransduction is the process by which cells sense mechanical stimuli such as
elasticity, viscosity, and nanotopography of extracellular matrix and translate them into …

[HTML][HTML] Localised and sustained intradermal delivery of methotrexate using nanocrystal-loaded microneedle arrays: Potential for enhanced treatment of psoriasis

IA Tekko, AD Permana, L Vora, T Hatahet… - European Journal of …, 2020 - Elsevier
Methotrexate (MTX), typically used as its sodium salt (MTX Na), is a first-line treatments for
moderate to severe psoriasis, showing good efficacy. However, its systemic administration is …

Development and characterisation of novel poly (vinyl alcohol)/poly (vinyl pyrrolidone)-based hydrogel-forming microneedle arrays for enhanced and sustained …

IA Tekko, G Chen, J Domínguez-Robles… - International journal of …, 2020 - Elsevier
Methotrexate (MTX) is one of the mainstays of treatment for rheumatoid arthritis (RA) and
juvenile idiopathic arthritis (JIA) and it is mainly administered either orally or by …

Nestorone nanosuspension-loaded dissolving microneedles array patch: a promising novel approach for “on-demand” hormonal female-controlled peritcoital …

E Altuntaş, IA Tekko, LK Vora, N Kumar… - International Journal of …, 2022 - Elsevier
Abstract “On demand” hormonal female-controlled pericoital contraception is one strategy
which could be used to minimize the impact of unintended pregnancy. Nestorone (NES) is a …

A review on nano Ti-based oxides for dark and photocatalysis: from photoinduced processes to bioimplant applications

CJ Querebillo - Nanomaterials, 2023 - mdpi.com
Catalysis on TiO2 nanomaterials in the presence of H2O and oxygen plays a crucial role in
the advancement of many different fields, such as clean energy technologies, catalysis …

[HTML][HTML] The effects of glycols on molecular mobility, structure, and permeability in stratum corneum

N Kis, M Gunnarsson, S Berkó, E Sparr - Journal of Controlled Release, 2022 - Elsevier
The skin provides an attractive alternative to the conventional drug administration routes.
Still, it comes with challenges as the upper layer of the skin, the stratum corneum (SC) …

Physical and biological properties of electrospun poly(d,l‐lactide)/nanoclay and poly(d,l‐lactide)/nanosilica nanofibrous scaffold for bone tissue engineering

F Lopresti, FC Pavia, M Ceraulo… - … Research Part A, 2021 - Wiley Online Library
Electrospun scaffolds exhibiting high physical performances with the ability to support cell
attachment and proliferation are attracting more and more scientific interest for tissue …

Spatio-temporal control of cell adhesion: toward programmable platforms to manipulate cell functions and fate

C Cimmino, L Rossano, PA Netti… - … in Bioengineering and …, 2018 - frontiersin.org
Biophysical and biochemical signals of material surfaces potently regulate cell functions and
fate. In particular, micro-and nano-scale patterns of adhesion signals can finely elicit and …

Development of D-α-Tocopherol polyethylene glycol 1000 succinate fabricated nanostructural lipid carrier of sorafenib tosylate for metastatic colorectal targeting …

S Bhattacharya, S Sharma, BG Prajapati - Frontiers in Oncology, 2022 - frontiersin.org
The study aimed to create D-α-Tocopherol polyethylene glycol 1000 succinate (TPGS)
nanostructured lipid carriers (NLC) of sorafenib tosylate (ST) as lymphatic delivery systems …