The array of end organ innervations of the vagus nerve, coupled with increased basic
science evidence, has led to vagus nerve stimulation (VNS) being explored as a …

Acetylcholinesterase (AChE) plays an important role in the pathogenesis of
neurodegenerative diseases by influencing the inflammatory response, apoptosis, oxidative …

Background Depression is the most common form of mental disorder in community and
health care settings and current treatments are far from satisfactory. Vagus nerve stimulation …

Nowadays, the worldwide interest is growing to use medicinal plants and their active
constituents to develop new potent medicines with fewer side effects. Precise dietary …

According to the recently proposed vigilance model of affective disorders (vigilance in the
sense of “brain arousal”), manic behaviour is partly interpreted as an autoregulatory attempt …

Background The amygdala is a key region in emotion processing, and studies have
suggested that amygdala-frontal functional connectivity deficits could be modulated by …

Rosmarinus officinalis (R. officinalis), a culinary aromatic and medicinal plant, is very rich in
polyphenols and flavonoids with high antioxidant properties. This plant was reported to exert …

Bipolar disorder is a unique illness characterized by fluctuations between mood states of
depression and mania. Originally, an adrenergic–cholinergic balance hypothesis was …

The root decoction of Cnestis ferruginea (CF) Vahl DC (Connaraceae) is used in traditional
African medicine in the management of psychiatric disorders. This study presents the …

Scopolamine produces rapid and significant symptom improvement in patients with
depression, and most notably in patients who do not respond to current antidepressant …