Brain metastases occur commonly in patients with advanced solid malignancies. Yet, less is
known about brain metastases than cancer-related entities of similar incidence. Advances in …

PURPOSE We report CNS efficacy of first-line osimertinib plus chemotherapy versus
osimertinib monotherapy in patients with epidermal growth factor receptor (EGFR)–mutated …

Simple Summary Decline in cognitive function is a major problem for patients undergoing
whole-brain radiotherapy (WBRT). Scientific interest has increased due to the high dropout …

Simple Summary Brain metastases (BMs) are the most common brain malignancy and are
projected to increase in incidence over the coming decades. Historically, brain metastasis …

Purpose Little is known about cancer-related cognitive impairments (CRCI) in women with
metastatic breast cancer (MBC). The purpose of this study is to (1) comprehensively …

Cognitive deficits occur in up to 90% of patients with brain metastases and can be caused by
the tumor itself and whole brain radiation therapy. Latest treatment options to reduce …

Abstract FLASH radiotherapy (FLASH RT) is a technique to deliver ultra-high dose rate in a
fraction of a second. Evidence from experimental animal models suggest that FLASH RT …

Traditionally, in the past, most of central nervous system metastases from solid tumors were
associated with an advanced phase of the disease needing palliation only, while to date …

Objective cognitive tests are the core component of neuropsychological evaluation and have
a critical role in clinical care and research regarding the cognitive impacts of brain tumors …

Cognitive symptoms are frequently reported by neuro-oncology patients across the
treatment trajectory. Patient-reported or subjective cognitive concerns have been shown to …