Han Chinese specific cytochrome P450 polymorphisms and their impact on the metabolism of anti-hypertensive drugs with adrenoreceptor blocking properties

JC Qian, JP Cai, GX Hu - Expert Opinion on Drug Metabolism & …, 2021 - Taylor & Francis
ABSTRACT Introduction: Cytochrome P450 (CYP) is a monooxygenase superfamily
mediating the elimination of anti-hypertensive drugs. Polymorphisms of CYP would lead to …

Pharmacist consult reports to support pharmacogenomics report interpretation

D Bright, C Saadeh, S DeVuyst-Miller… - Pharmacogenomics …, 2020 - Taylor & Francis
Background The clinical implementation of pharmacogenomics (PGx) has often involved
teams that include pharmacists. PGx laboratories often provide baseline information within …

Precision medicine—nobody is average

AA Vinks - Clinical Pharmacology & Therapeutics, 2017 - Wiley Online Library
Medicine gets personal and tailor‐made treatments are underway. Hospitals have started to
advertise their advanced genomic testing capabilities and even their disruptive technologies …

A research agenda to support the development and implementation of genomics-based clinical informatics tools and resources

K Wiley, L Findley, M Goldrich… - Journal of the …, 2022 - academic.oup.com
Abstract Objective The Genomic Medicine Working Group of the National Advisory Council
for Human Genome Research virtually hosted its 13th genomic medicine meeting titled …

Clinical guidelines and implementation into daily dental practice

GN Guncu, SK Nemli, E Carrilho… - Acta medica …, 2018 - actamedicaportuguesa.com
Introduction: The purpose of this study is to assess the extent of the familiarity, attitude and
perceptions of dental professionals regarding clinical dental guidelines and their …

[HTML][HTML] Pharmacogenomics, how to deal with different types of variants in next generation sequencing data in the personalized medicine area

A Tafazoli, N Wawrusiewicz-Kurylonek… - Journal of Clinical …, 2020 - mdpi.com
Pharmacogenomics (PGx) is the knowledge of diverse drug responses and effects in
people, based on their genomic profiles. Such information is considered as one of the main …

[HTML][HTML] A web-based pharmacogenomics search tool for precision medicine in perioperative care

S Zarei, Y Costas, G Orozco, M Zaydlin, A Mirtar… - Journal of Personalized …, 2020 - mdpi.com
Background: Precision medicine represents an evolving approach to improve treatment
efficacy by modifying it to individual patient's gene variation. Pharmacogenetics, an …

Problems and promises: How to tell the story of a Genome Wide Association Study?

C Heeney - Studies in History and Philosophy of Science Part A, 2021 - Elsevier
The promise of treatments for common complex diseases (CCDs) is understood as an
important force driving large scale genetics research over the last few decades. This paper …

Genetic and genomic competencies for nursing informatics internationally

KA Mc Cormick, KA Calzone - … for Nurses in the Future of …, 2017 - ebooks.iospress.nl
The majority of health professionals now have genetic and genomic competencies and
some are measured by certification standards. Nursing has a proud history of defining roles …

Building an information system to facilitate pharmacogenomics clinical translation with clinical decision support

W Qin, X Lu, Q Shu, H Duan, H Li - Pharmacogenomics, 2022 - Taylor & Francis
Pharmacogenomics clinical decision support (PGx-CDS) is an important tool to incorporate
PGx information into existing clinical workflows and facilitate PGx clinical translation …