Natural products from mangrove sediments-derived microbes: Structural diversity, bioactivities, biosynthesis, and total synthesis

K Li, S Chen, X Pang, J Cai, X Zhang, Y Liu… - European Journal of …, 2022 - Elsevier
The mangrove forests are a complex ecosystem, and the microbial communities in
mangrove sediments play a critical role in the biogeochemical cycles of mangrove …

Unusual secondary metabolites from the mangrove ecosystems: Structures, bioactivities, chemical, and bio-syntheses

MJ Wu, B Xu, YW Guo - Marine Drugs, 2022 - mdpi.com
Mangrove ecosystems are widely distributed in the intertidal zone of tropical and subtropical
estuaries or coasts, containing abundant biological communities, for example, mangrove …

Computational identification of drug-like marine natural products as potential RNA polymerase inhibitors against Nipah virus

JM Abduljalil, AA Elfiky, ESTA Sayed… - … Biology and Chemistry, 2023 - Elsevier
Nipah virus (NiV) has been an alarming threat to human populations in southern Asia for
more than a decade. It is one of the most deadly viruses in the Mononegavirales order …

Integrating taxonomic and chemical diversity of mangrove-associated ascomycetes to discover or repurpose bioactive natural products

IY Martínez-Aldino, J Rivera-Chávez… - Journal of Natural …, 2023 - ACS Publications
Natural product reisolation is a bottleneck when discovering new bioactive chemical entities
from nature. To overcome this issue, multi-informative approaches integrating several layers …

Unexpected Noremestrin with a Sulfur-Bearing 15-Membered Macrocyclic Lactone from Emericella sp. 1454

Y Chen, T Xiao, S Guo, S Chang, X Xi, B Su… - Organic …, 2023 - ACS Publications
Two previous unreported epipolythiodioxopiperazines of the emestrin family, namely,
noremestrin A (1) and secoemestrin E (2), were successfully isolated from the fungal source …

New Chlorinated Metabolites and Antiproliferative Polyketone from the Mangrove Sediments-Derived Fungus Mollisia sp. SCSIO41409

J Cai, X Wang, X Gan, Q Zhou, X Luo, B Yang, Y Liu… - Marine Drugs, 2022 - mdpi.com
Two new chlorinated metabolites, 8-chlorine-5-hydroxy-2, 3-dimethyl-7-methoxychromone
(1) and 3, 4-dichloro-1 H-pyrrole-2, 5-dione (3), and eight known compounds (2 and 4–9) …

Marine Aspergillus: A Treasure Trove of Antimicrobial Compounds

H Li, Y Fu, F Song - Marine Drugs, 2023 - mdpi.com
Secondary metabolites from marine organisms are diverse in structure and function. Marine
Aspergillus is an important source of bioactive natural products. We reviewed the structures …

Microbial metabolites beneficial to plant hosts across ecosystems

V Mathur, D Ulanova - Microbial Ecology, 2023 - Springer
Plants are intimately connected with their associated microorganisms. Chemical interactions
via natural products between plants and their microbial symbionts form an important aspect …

Metabolomics-Guided Discovery of New Dimeric Xanthones from Co-Cultures of Mangrove Endophytic Fungi Phomopsis asparagi DHS-48 and Phomopsis sp. DHS …

J Wu, D Chen, Q Li, T Feng, J Xu - Marine Drugs, 2024 - mdpi.com
The co-culture strategy, which mimics natural ecology by constructing an artificial microbial
community, is a useful tool for the activation of biosynthetic gene clusters (BGCs) to generate …

New Sorbicillinoids from the Mangrove Endophytic Fungus Trichoderma reesei SCNU-F0042

J Li, T Chen, J Yu, H Jia, C Chen, Y Long - Marine Drugs, 2023 - mdpi.com
Three new dimeric sorbicillinoids (1–3) and one new 3, 4, 6-trisubstituted α-pyrone (5),
along with seven analogues (4 and 6–11), were isolated from the mangrove endophytic …