Single nucleotide polymorphisms (SNPs) in the FK506 binding protein 5 (FKBP5) gene
combine with traumatic events to increase risk for post-traumatic stress and major …

Depression is frequent in older individuals and is often associated with cognitive impairment
and increasing risk of subsequent dementia. Late-life depression (LLD) has a negative …

Abstract Major Depressive Disorder (MDD) is common and disabling, and is linked to
functional impairment and increased mortality. While current treatments for MDD are …

The growing prevalence of neurodegenerative disorders associated with aging and
cognitive decline has generated increasing cross-disciplinary interest in non …

This systematic review sources the latest neuroimaging evidence for the role of cognition-
related brain networks in depression, and relates their abnormal functioning to symptoms of …

Background Physical exercise is increasingly recognized as a treatment for major
depression, even among older patients. However, it is still unknown which depressive …

Objective The clinical profile of late-life depression (LLD) is frequently associated with
cognitive impairment, aging-related brain changes, and somatic comorbidity. This two-site …

Sleep disturbance is prevalent in older adults, particularly so in those at a greater risk of
dementia. However, so far the clinical, medical and neuropsychological correlates of …

Background Depression later in life may have a more somatic presentation compared with
depression earlier in life due to chronic somatic disease and increasing age. This study …

Background A comprehensive assessment of catatonic symptoms is decisive for diagnosis,
neuronal correlates, and evaluation of treatment response and prognosis of catatonia …