Acrylamide (ACR) is an axonal toxicant that produces peripheral neuropathy in laboratory
animals and humans. Epidemiological study found that diet ACR exposure was associated …

Background After 30 years of consensus-derived diagnostic categories in mental health, it is
time to head in new directions. Those categories placed great emphasis on enhanced …

Background: The goals of this study were to establish prevalence of subjective memory
complaints (SMC) and depressive symptoms (DS) and their relation to cognitive functioning …

Background Depression is a mental disorder characterized by a pervasive low mood and
loss of pleasure or interest in usual activities, and often results in cognitive dysfunction. The …

Objectives Late-life major depression (LLD) is characterized by distinct epidemiologic and
psychosocial factors, as well as medical comorbidities that are associated with specific …

Although genuine motor abnormalities (GMA) are frequently found in schizophrenia, they
are also considered as an intrinsic feature of bipolar, obsessive-compulsive, and …

Background The management of late‐life depression is challenged by high rates of
treatment‐resistance and adverse effects, along with medical comorbidities and …

Antidepressant outcomes in older adults with depression is poor, possibly because of
comorbidities such as cerebrovascular disease. Therefore, we leveraged multiple genome …

Background Although evidence suggests that there are neurobiological differences between
unipolar depression in younger versus older adults, conflicting evidence exists about …

Background Oxidative stress (OS) has been implicated in the pathophysiology of late-life
depression (LLD). Mitochondria are the primary source of oxidative stress and can be …