[HTML][HTML] Role of oxidative stress in male infertility: an updated review

AT Alahmar - Journal of human reproductive sciences, 2019 - journals.lww.com
Current evidence links oxidative stress (OS) to male infertility, reduced sperm motility, sperm
DNA damage and increased risk of recurrent abortions and genetic diseases. A review of …

Oxidative stress and male infertility

S Bisht, M Faiq, M Tolahunase, R Dada - Nature Reviews Urology, 2017 - nature.com
DNA damage, largely owing to oxidative stress, is a leading cause of defective sperm
function. High levels of oxidative stress result in damage to sperm DNA, RNA transcripts …

Reactive oxygen species as mediators of sperm capacitation and pathological damage

RJ Aitken - Molecular reproduction and development, 2017 - Wiley Online Library
Oxidative stress plays a major role in the life and death of mammalian spermatozoa. These
gametes are professional generators of reactive oxygen species (ROS), which appear to …

[HTML][HTML] Male subfertility and oxidative stress

EPP Evans, JTM Scholten, A Mzyk… - Redox biology, 2021 - Elsevier
To date 15% of couples are suffering from infertility with 45–50% of males being
responsible. With an increase in paternal age as well as various environmental and lifestyle …

[HTML][HTML] The importance of oxidative stress in determining the functionality of mammalian spermatozoa: a two-edged sword

RJ Aitken, JR Drevet - Antioxidants, 2020 - mdpi.com
This article addresses the importance of oxidative processes in both the generation of
functional gametes and the aetiology of defective sperm function. Functionally, sperm …

Causes and consequences of oxidative stress in spermatozoa

RJ Aitken, Z Gibb, MA Baker, J Drevet… - Reproduction, Fertility …, 2016 - CSIRO Publishing
Spermatozoa are highly vulnerable to oxidative attack because they lack significant
antioxidant protection due to the limited volume and restricted distribution of cytoplasmic …

[HTML][HTML] Systematic review of antioxidant types and doses in male infertility: Benefits on semen parameters, advanced sperm function, assisted reproduction and live …

A Majzoub, A Agarwal - Arab journal of urology, 2018 - Elsevier
Objective To explore the current evidence concerning the effect of oral antioxidant
supplementation on various male fertility outcomes, as antioxidants are widely available …

[HTML][HTML] Male infertility testing: reactive oxygen species and antioxidant capacity

EY Ko, ES Sabanegh Jr, A Agarwal - Fertility and sterility, 2014 - Elsevier
Reactive oxygen species (ROS) are an integral component of sperm developmental
physiology, capacitation, and function. Elevated ROS levels, from processes such as …

Impacts of oxidative stress and antioxidants on semen functions

AK Bansal, GS Bilaspuri - Veterinary medicine international, 2011 - Wiley Online Library
Oxidative stress (OS) has been considered a major contributory factor to the infertility.
Oxidative stress is the result of imbalance between the reactive oxygen species (ROS) and …

The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology

K Bedard, KH Krause - Physiological reviews, 2007 - journals.physiology.org
For a long time, superoxide generation by an NADPH oxidase was considered as an oddity
only found in professional phagocytes. Over the last years, six homologs of the cytochrome …