Human microbiome myths and misconceptions

AW Walker, L Hoyles - Nature microbiology, 2023 - nature.com
Over the past two decades, interest in human microbiome research has increased
exponentially. Regrettably, this increased activity has brought with it a degree of hype and …

Bench to bedside—new insights into the pathogenesis of necrotizing enterocolitis

DJ Hackam, CP Sodhi - Nature reviews Gastroenterology & hepatology, 2022 - nature.com
Necrotizing enterocolitis (NEC) is the leading cause of death and disability from
gastrointestinal disease in premature infants. Recent discoveries have shed light on a …

Supplementation with a probiotic mixture accelerates gut microbiome maturation and reduces intestinal inflammation in extremely preterm infants

J Samara, S Moossavi, B Alshaikh, VA Ortega… - Cell host & …, 2022 - cell.com
Probiotics are increasingly administered to premature infants to prevent necrotizing
enterocolitis and neonatal sepsis. However, their effects on gut microbiome assembly and …

Multi-kingdom ecological drivers of microbiota assembly in preterm infants

C Rao, KZ Coyte, W Bainter, RS Geha, CR Martin… - Nature, 2021 - nature.com
The gut microbiota of preterm infants develops predictably,,,,,–, with pioneer species
colonizing the gut after birth, followed by an ordered succession of microorganisms. The gut …

The human microbiome and child growth–first 1000 days and beyond

RC Robertson, AR Manges, BB Finlay… - Trends in …, 2019 - cell.com
The assembly of microbial communities within the gastrointestinal tract during early life plays
a critical role in immune, endocrine, metabolic, and other host developmental pathways …

Gut microbiota: Role in pathogen colonization, immune responses, and inflammatory disease

JM Pickard, MY Zeng, R Caruso… - Immunological …, 2017 - Wiley Online Library
The intestinal tract of mammals is colonized by a large number of microorganisms including
trillions of bacteria that are referred to collectively as the gut microbiota. These indigenous …

The multifaceted roles of breast milk antibodies

C Atyeo, G Alter - Cell, 2021 - cell.com
Neonates are born with an immature immune system and rely on the transfer of immunity
from their mothers. Maternal antibodies are transferred via the placenta and breast milk …

Probiotics, prebiotics and amelioration of diseases

YL Tsai, TL Lin, CJ Chang, TR Wu, WF Lai… - Journal of biomedical …, 2019 - Springer
Dysbiosis of gut microbiota is closely related to occurrence of many important chronic
inflammations-related diseases. So far the traditionally prescribed prebiotics and probiotics …

The role of the microbiome in the developmental origins of health and disease

LT Stiemsma, KB Michels - Pediatrics, 2018 - publications.aap.org
Although the prominent role of the microbiome in human health has been established, the
early-life microbiome is now being recognized as a major influence on long-term human …

Maternal IgA protects against the development of necrotizing enterocolitis in preterm infants

KP Gopalakrishna, BR Macadangdang, MB Rogers… - Nature medicine, 2019 - nature.com
Neonates are protected from colonizing bacteria by antibodies secreted into maternal milk.
Necrotizing enterocolitis (NEC) is a disease of neonatal preterm infants with high morbidity …