Type 2 immunity in the skin and lungs

CA Akdis, PD Arkwright, MC Brüggen, W Busse… - Allergy, 2020 - Wiley Online Library
There has been extensive progress in understanding the cellular and molecular
mechanisms of inflammation and immune regulation in allergic diseases of the skin and …

Advances and highlights in biomarkers of allergic diseases

I Ogulur, Y Pat, O Ardicli, E Barletta, L Cevhertas… - Allergy, 2021 - Wiley Online Library
During the past years, there has been a global outbreak of allergic diseases, presenting a
considerable medical and socioeconomical burden. A large fraction of allergic diseases is …

[HTML][HTML] New perspectives in food allergy

M De Martinis, MM Sirufo, M Suppa… - International journal of …, 2020 - mdpi.com
The improvement of the knowledge of the pathophysiological mechanisms underlying the
tolerance and sensitization to food antigens has recently led to a radical change in the …

COVID‐19 pandemic: practical considerations on the organization of an allergy clinic—an EAACI/ARIA Position Paper

O Pfaar, L Klimek, M Jutel, CA Akdis, J Bousquet… - Allergy, 2021 - Wiley Online Library
Background The coronavirus disease 2019 (COVID‐19) has evolved into a pandemic
infectious disease transmitted by the severe acute respiratory syndrome coronavirus (SARS …

Biomarkers for diagnosis and prediction of therapy responses in allergic diseases and asthma

H Breiteneder, YQ Peng, I Agache, Z Diamant… - Allergy, 2020 - Wiley Online Library
Modern health care requires a proactive and individualized response to diseases,
combining precision diagnosis and personalized treatment. Accordingly, the approach to …

Roles of follicular helper and regulatory T cells in allergic diseases and allergen immunotherapy

Y Yao, CL Chen, D Yu, Z Liu - Allergy, 2021 - Wiley Online Library
Allergic diseases are characterized by overactive type 2 immune responses to allergens and
immunoglobulin E (IgE)‐mediated hypersensitivity. Emerging evidence suggests that …

Biomarkers of diagnosis and resolution of food allergy

RX Foong, AF Santos - Pediatric Allergy and Immunology, 2021 - Wiley Online Library
Food allergy is increasing in prevalence, affecting up to 10% of children in developed
countries. Food allergy can significantly affect the quality of life and well‐being of patients …

Immunological resilience and biodiversity for prevention of allergic diseases and asthma

T Haahtela, H Alenius, J Lehtimäki, A Sinkkonen… - Allergy, 2021 - Wiley Online Library
Increase of allergic conditions has occurred at the same pace with the Great Acceleration,
which stands for the rapid growth rate of human activities upon earth from 1950s. Changes …

[HTML][HTML] Mechanisms of microbe-immune system dialogue within the skin

N Lunjani, S Ahearn-Ford, FS Dube, C Hlela… - Genes & …, 2021 - nature.com
The prevalence and severity of dermatological conditions such as atopic dermatitis have
increased dramatically during recent decades. Many of the factors associated with an …

[HTML][HTML] Intestinal mucus barrier: a missing piece of the puzzle in food allergy

A Parrish, M Boudaud, A Kuehn, M Ollert… - Trends in Molecular …, 2022 - cell.com
The prevalence of food allergies has reached epidemic levels but the cause remains largely
unknown. We discuss the clinical relevance of the gut mucosal barrier as a site for allergic …