Advances and prospects in the treatment of pancreatic cancer

H Duan, L Li, S He - International journal of nanomedicine, 2023 - Taylor & Francis
Pancreatic cancer is a highly malignant and incurable disease, characterized by its
aggressive nature and high fatality rate. The most common type is pancreatic ductal …

Intratumoural microbiota: a new frontier in cancer development and therapy

Y Cao, H Xia, X Tan, C Shi, Y Ma, D Meng… - … and Targeted Therapy, 2024 - nature.com
Human microorganisms, including bacteria, fungi, and viruses, play key roles in several
physiological and pathological processes. Some studies discovered that tumour tissues …

[HTML][HTML] Metabolomics of extracellular vesicles: a future promise of multiple clinical applications

YL Wu, WJ Chen, M Guo, Q Tan, E Zhou… - International Journal …, 2022 - ncbi.nlm.nih.gov
Extracellular vesicles (EVs) can contain DNA, RNA, proteins and metabolic molecules from
primary origins; they are coated with a phospholipid bilayer membrane and released by …

Intratumoral microbiota: A new force in diagnosing and treating pancreatic cancer

Z Jiang, W Zhang, Z Zhang, G Sha, D Wang, D Tang - Cancer Letters, 2023 - Elsevier
Pancreatic cancer is an increasingly growing source of cancer-related deaths and is often
diagnosed at advanced stages. Its treatment is difficult because of the poor results of …

[HTML][HTML] Application of microfluidic technology based on surface-enhanced Raman scattering in cancer biomarker detection: A review

C Nie, I Shaw, C Chen - Journal of Pharmaceutical Analysis, 2023 - Elsevier
With the continuous discovery and research of predictive cancer-related biomarkers, liquid
biopsy shows great potential in cancer diagnosis. Surface-enhanced Raman scattering …

Emerging role of pancreatic stellate cell-derived extracellular vesicles in pancreatic cancer

R Sarkar, Z Xu, CJ Perera, MV Apte - Seminars in cancer biology, 2023 - Elsevier
Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive cancer that is
characterised by a prominent collagenous stromal reaction/desmoplasia surrounding …

Extracellular vesicle-mediated ferroptosis, pyroptosis, and necroptosis: potential clinical applications in cancer therapy

YC Yang, Q Jiang, KP Yang, L Wang, G Sethi… - Cell Death Discovery, 2024 - nature.com
Extracellular vesicles (EVs) have gained increasing recognition as significant regulators of
intercellular communication in various physiological and pathological processes. These …

Extracellular vesicles in gastric cancer: role of exosomal lncRNA and microRNA as diagnostic and therapeutic targets

C Jiang, J Zhang, W Wang, Z Shan, F Sun… - Frontiers in …, 2023 - frontiersin.org
Extracellular vesicles (EVs), including exosomes, play a crucial role in intercellular
communication and have emerged as important mediators in the development and …

Piceatannol induces apoptotic cell death through activation of caspase-dependent pathway and upregulation of ROS-mediated mitochondrial dysfunction in …

İ Çınar Ayan, E Güçlü, H Vural, HG Dursun - Molecular biology reports, 2022 - Springer
Background Piceatannol is a naturally occurring plant-derived phenolic compound
(stilbenoid), an analogue of resveratrol. It has been shown that, piceatannol has biological …

The preliminary exploration of what role miRNAs derived from urinary exosomes play in kidney stone formation

Y Yang, Q Wang, Y Xun, C Li, S Wang - Urology, 2022 - Elsevier
OBJECTIVE To identify dysregulated microRNAs (miRNAs) derived from urinary small
Extracellular Vesicles (sEVs) and to explore the potential roles sEVs miRNAs play in …