Antimicrobial resistance: two-component regulatory systems and multidrug efflux pumps

GV De Gaetano, G Lentini, A Famà, F Coppolino… - Antibiotics, 2023 - mdpi.com
The number of multidrug-resistant bacteria is rapidly spreading worldwide. Among the
various mechanisms determining resistance to antimicrobial agents, multidrug efflux pumps …

The Plasmidomic Landscape of Clinical Methicillin-Resistant Staphylococcus aureus Isolates from Malaysia

EI Al-Trad, CH Chew, AM Che Hamzah, Z Suhaili… - Antibiotics, 2023 - mdpi.com
Methicillin-resistant Staphylococcus aureus (MRSA) is a priority nosocomial pathogen with
plasmids playing a crucial role in its genetic adaptability, particularly in the acquisition and …

Synthesis, nanostructuring and in silico studies of a new imine bond containing a macroheterocycle as a promising PBP-2a non-β-lactam inhibitor

A Huseynzada, M Aghayev, S Hajiyeva… - Journal of Materials …, 2023 - pubs.rsc.org
This study is devoted to the synthesis of a 40-membered macroheterocycle with its further
nanostructuring by magnetite nanoparticles. The mentioned macroheterocycle was …

Occurrence, antimicrobial susceptibility, and resistance genes of Staphylococcus aureus in milk and milk products in the Arsi highlands of Ethiopia

A Deddefo, G Mamo, M Asfaw, A Edao, A Hiko, D Fufa… - BMC microbiology, 2024 - Springer
Abstract Background In Ethiopia, milk production and handling practices often lack proper
hygiene measures, leading to the potential contamination of milk and milk products with …

Potential Surviving Effect of Cleome droserifolia Extract against Systemic Staphylococcus aureus Infection: Investigation of the Chemical Content of the Plant

J Alqahtani, WA Negm, E Elekhnawy, IA Hussein… - Antibiotics, 2024 - mdpi.com
The increasing rates of morbidity and mortality owing to bacterial infections, particularly
Staphylococcus aureus have necessitated finding solutions to face this issue. Thus, we …

Synthesis, antibacterial potential and in silico molecular docking analysis of triazene compounds via diazo coupling reactions of an amine

AN Abd Halim, ASM Hussin, Z Ngaini… - Tetrahedron …, 2023 - Elsevier
In the drug discovery and development process, structure-based drug design is essential to
ensuring the effectiveness and efficiency of the drugs towards the target receptor. The …

Comparative De Novo and Pan-Genome Analysis of MDR Nosocomial Bacteria Isolated from Hospitals in Jeddah, Saudi Arabia

M Alghamdi, E Al-Judaibi, M Al-Rashede, A Al-Judaibi - Microorganisms, 2023 - mdpi.com
Multidrug-resistant (MDR) bacteria are one of the most serious threats to public health, and
one of the most important types of MDR bacteria are those that are acquired in a hospital …

[HTML][HTML] Neonatal methicillin-resistant Staphylococcus aureus pneumonia–related recurrent fatal pyopneumothorax: A case report and review of literature

XC Li, L Sun, T Li - World Journal of Clinical Cases, 2023 - ncbi.nlm.nih.gov
BACKGROUND Although neonatal Staphylococcus aureus pneumonia is common and
usually curable, it can also be refractory and life-threatening. Herein, we report a case of …

[PDF][PDF] Nasal Carriage and Antimicrobial Susceptibility Pattern of Staphylococcus aureus among Breastfeeding Mothers and their Infants.

R Syahniar, A Anandani… - Journal of Pure & …, 2024 - pdfs.semanticscholar.org
Most S. aureus infections are multidrug resistant. S. aureus infections often occur with
prolonged conditions, causing increased treatment costs and mortality rates. There is a need …