Retracted: Evaluation of antidiabetic activity of biologically synthesized silver nanoparticles using Pouteria sapota in streptozotocin‐induced diabetic rats: 在链脲霉素 …

S Prabhu, S Vinodhini, C Elanchezhiyan… - Journal of …, 2018 - Wiley Online Library
摘要背景药用植物以及绿色合成的银纳米颗粒(silver nanoparticles, AgNPs)
目前都已被证实是有效治疗糖尿病的药物来源. 当前这项研究聚焦于来源于山榄果水叶提取物的 …

The place of dipeptidyl peptidase‐4 inhibitors in type 2 diabetes therapeutics: A “me too” or “the special one” antidiabetic class?

R Godinho, C Mega… - Journal of diabetes …, 2015 - Wiley Online Library
Incretin‐based therapies, the most recent therapeutic options for type 2 diabetes mellitus
(T2DM) management, can modify various elements of the disease, including hypersecretion …

Sitagliptin: a review of its use in patients with type 2 diabetes mellitus

GL Plosker - Drugs, 2014 - Springer
Abstract Sitagliptin (Januvia®, Xelevia™, Glactiv®, Tesavel®) is an orally administered,
potent and highly selective inhibitor of dipeptidyl peptidase-4 (DPP-4) and was the first …

NRF2 activation by antioxidant antidiabetic agents accelerates tumor metastasis

H Wang, X Liu, M Long, Y Huang, L Zhang… - Science translational …, 2016 - science.org
Cancer is a common comorbidity of diabetic patients; however, little is known about the
effects that antidiabetic drugs have on tumors. We discovered that common classes of drugs …

Dipeptidyl peptidase-4 inhibitors and heart failure: a meta-analysis of randomized clinical trials

M Monami, I Dicembrini, E Mannucci - Nutrition, Metabolism and …, 2014 - Elsevier
Background & aims Recently, the SAVOR TIMI-53 (Saxagliptin Assessment of Vascular
Outcomes Recorded in patients with diabetes mellitus–Thrombolysis in Myocardial Infarction …

Safety and tolerability of sitagliptin in type 2 diabetes: pooled analysis of 25 clinical studies

SS Engel, E Round, GT Golm, KD Kaufman… - Diabetes Therapy, 2013 - Springer
Introduction In a previous pooled analysis of 19 double-blind clinical studies conducted by
Merck, which included data available as of July 2009 on 10,246 patients with type 2 …

Exploring the effects of DPP-4 inhibitors on the kidney from the bench to clinical trials

G Coppolino, C Leporini, L Rivoli, F Ursini… - Pharmacological …, 2018 - Elsevier
Abstract Dipeptidyl-peptidase-4 (DPP-4) inhibitors are a relatively new class of non-insulin
glucose-lowering agents, belonging to the incretin family, which are able to improve …

Dipeptidyl peptidase-4 inhibitors and gallbladder or biliary disease in type 2 diabetes: systematic review and pairwise and network meta-analysis of randomised …

L He, J Wang, F Ping, N Yang, J Huang, W Li, L Xu… - bmj, 2022 - bmj.com
Objective To examine the association between dipeptidyl peptidase-4 inhibitors and
gallbladder or biliary diseases. Design Systematic review and pairwise and network meta …

DPP‐4 inhibitors and risk of infections: a meta‐analysis of randomized controlled trials

W Yang, X Cai, X Han, L Ji - Diabetes/Metabolism Research …, 2016 - Wiley Online Library
Background To evaluate the risk of infections in the treatment of type 2 diabetes patients with
dipeptidyl‐peptidase 4 (DPP‐4) inhibitors. Methods A literature search was conducted …

Cardiovascular safety of sitagliptin in patients with type 2 diabetes mellitus: a pooled analysis

SS Engel, GT Golm, D Shapiro, MJ Davies… - Cardiovascular …, 2013 - Springer
Objective To compare the incidence of cardiovascular events and mortality in patients with
type 2 diabetes mellitus treated with sitagliptin or non-sitagliptin comparators. Methods A …