Obesity prevalence, particularly in children and young adults, is perilously increasing
worldwide foreseeing serious negative health impacts in the future to come. Obesity is linked …

Non-Alcoholic Fatty Liver Disease (NAFLD) is the most common form of chronic liver
disease. The histological spectrum of NAFLD ranges from simple steatosis to chronic …

Natural killer (NK) cells kill mutant cells through death receptors and cytotoxic granules,
playing an essential role in controlling cancer progression. However, in the tumor …

Asthma is a heterogeneous disease, with multiple underlying inflammatory pathways and
structural airway abnormalities that impact disease persistence and severity. Recent …

Nearly 70% of adults in the US are currently overweight or obese. Despite such high
prevalence, the impact of obesity on antitumor immunity and immunotherapy outcomes …

Natural Killer (NK) cells acquire memory-like properties following a brief stimulation with IL-
12, IL-15 and IL-18. These IL-12/15/18-preactivated NK cells, also known as cytokine …

Immunotherapy shifted the paradigm of cancer treatment. The clinical approval of immune
checkpoint blockade and adoptive cell transfer led to considerable success in several tumor …

Mesenchymal stem cell (MSC) therapy is an emerging treatment strategy to counteract
metabolic syndromes, including obesity and its comorbid disorders. However, its …

Abstract Purpose of Review In this review, we update the latest findings on the impacts of FA
metabolism reprogramming on the phenotypes and functions of immune cells in tumor …

Cancer progression generates a chronic inflammatory state that dramatically influences
hematopoiesis, originating different subsets of immune cells that can exert pro-or anti-tumor …