Impaired regulation of immune responses in cognitive decline and Alzheimer's disease: lessons from genetic association studies

M Chiappelli, E Tumini, E Porcellini… - Expert review of …, 2006 - Taylor & Francis
Altered levels of cytokines and acute-phase proteins have been described in the blood and
brain of patients with Alzheimer's disease. Microglia are resident cells of the brain and …

白细胞介素-6 基因-174G/C 多态性与阿尔茨海默病及血管性痴呆的关联研究

饶冬萍, 唐牟尼, 马崔, 郭扬波, 韩海英, 林育华 - 中华精神科杂志, 2008 - cqvip.com
目的探索白细胞介素-6 (IL-6) 基因启动子区-174G/C 多态性与阿尔茨海默病(AD),
血管性痴呆(VD) 的关系. 方法采取病例对照研究方法, 以广州地区流行病学调查中诊断的161 …

IL-6 启动子多态性与阿尔茨海默氏病的相关性探讨

张涌, 崔才三 - 山东医药, 2003 - cqvip.com
目的探讨细胞因子白介素6 (IL-6) 与阿尔茨海默氏病(AD) 的相关性. 方法用PCR-RFLP
技术检测356 例英国AD 患者和434 例对照者IL-6 启动子-174C/G 多态性, 并进行了对比分析 …

+ 874 (T→ A) single nucleotide gene polymorphism does not represent a risk factor for Alzheimer's disease

L Galimberti, B Arosio, C Calabresi, S Scurati… - Immunity & …, 2004 - Springer
In the recent years, several cytokines have been associated with Alzheimer's disease (AD)
development and progression and many studies have correlated this risk with …

[引用][C] Genomic analysis of the interleukin-1β-511 and interleukin-6-174 gene polymorphisms in Turkish patients with epilepsy

İ Gök, V Esen, HK Ozlece - Genetics and Molecular Research, 2014

IL-6 genotype and the susceptibility to Alzheimer's disease

PG Sand - International Journal of Neuroscience, 2015 - Taylor & Francis
I have read with interest the recent article by Hua and coworkers [1] on a putative protective
effect of an IL-6 “-174CC” genotype regarding Alzheimer's disease in Asian populations. In …

Cytokine gene polymorphisms in organ and haematopoietic stem cell transplantation

L Karabon - Advances in Hygiene and Experimental Medicine, 2004 - phmd.pl
The development of molecular biological techniques during the last decade has led to the
recognition of a series of polymorphic sites in the regulatory regions of cytokine-encoding …

[PDF][PDF] Association of pro-inflammatory cytokine gene polymorphisms with Parkinson's disease in Chinese population

W Hu, Y Chen, H Zhao - Int J Clin Exp Med, 2017 - e-century.us
The progressive neurodegenerative process in Parkinson's disease (PD) is accompanied by
chronic inflammation, including activation of microglia and astrocytes that express pro …

[PDF][PDF] Análise de polimorfismos genéticos em pacientes com alterações degenerativas da articulação temporomandibular

MIG Campos - Faculdade de Odontologia de Piracicaba …, 2007 - repositorio.unicamp.br
RESUMO O objetivo deste estudo foi investigar a ocorrência dos polimorfismos IL-1A (-
889C/T), IL-1B (-511C/T), IL-1B (+ 3953C/T), IL-1RN VNTR (intron 2), IL-6 (-174G/C) e TNF …

Markers of alzheimers disease

M Clerici, G Annoni, B Arosio - US Patent App. 14/149,362, 2014 - Google Patents
An inflammatory process is suggested to be involved in the pathogenesis of Alzheimer's
disease (AD), a neurodegenerative disorder characterized by the presence of neuritic …