Background Extraventricular neurocytoma at the sellar region (EVNSR) is an exceedingly
rare tumor. Given the paucity of specificity and its peculiar nature, our study aimed to …

Nonfunctioning pituitary neuroendocrine tumors (NF-PitNETs) are tumors that are not
associated with clinical evidence of hormonal hypersecretion. According to the World Health …

Pituitary neuroendocrine tumors (pitNETs) are the second most common primary brain
tumors. Despite their prevalence, the tumor immune microenvironment (TIME) and its clinical …

Growth Hormone-secreting adenomas exhibits variable biological behavior and
heterogeneous natural history, ranging from small adenomas and mild disease, to invasive …

Pituitary carcinoma (PC) is a rare, aggressive malignancy that comprises 0.1–0.2% of all
pituitary tumors. PC is defined anatomically as a pituitary tumor that metastasizes outside the …

Background Approximately 35% of pituitary adenoma (PA) display an aggressive profile,
resulting in low surgical total resection rates, high recurrence rates, and worse prognosis …

Gonadotroph cell adenoma is the most common clinically nonfunctioning pituitary adenoma;
and is pathologically defined by immunopositivity for SF-1, GATA2 and ER-α. Most tumors …

Folliculostellate cells are S100B-expressing cells with numerous functions in the normal
anterior pituitary. These cells have also been identified in pituitary neuroendocrine tumours …

Introduction Brain cancer is a debilitating disease with a poor survival rate. There are
significant challenges for effective treatment due to the presence of the blood–brain barrier …

Simple Summary The treatment of aggressive and metastatic pituitary neuroendocrine
tumors (PitNETs) refractory to current therapies, including temozolomide, is challenging and …