[HTML][HTML] The updated landscape of tumor microenvironment and drug repurposing
Accumulating evidence shows that cellular and acellular components in tumor
microenvironment (TME) can reprogram tumor initiation, growth, invasion, metastasis, and …
microenvironment (TME) can reprogram tumor initiation, growth, invasion, metastasis, and …
The Role of Cardioprotection in Cancer Therapy Cardiotoxicity: JACC: CardioOncology State-of-the-Art Review
Cardiotoxicity is a relatively frequent and potentially serious side effect of traditional and
targeted cancer therapies. Both general measures and specific pharmacologic …
targeted cancer therapies. Both general measures and specific pharmacologic …
[HTML][HTML] Mechanisms of anthracycline-induced cardiotoxicity: is mitochondrial dysfunction the answer?
A Murabito, E Hirsch, A Ghigo - Frontiers in cardiovascular medicine, 2020 - frontiersin.org
Cardiac side effects are a major drawback of anticancer therapies, often requiring the use of
low and less effective doses or even discontinuation of the drug. Among all the drugs known …
low and less effective doses or even discontinuation of the drug. Among all the drugs known …
Cardioprotection using strain-guided management of potentially cardiotoxic cancer therapy: 3-year results of the SUCCOUR trial
T Negishi, P Thavendiranathan, M Penicka… - Cardiovascular …, 2023 - jacc.org
Background Global longitudinal strain (GLS) can predict cancer therapeutics–related
cardiac dysfunction and guide initiation of cardioprotection (CPT). Objectives In this study …
cardiac dysfunction and guide initiation of cardioprotection (CPT). Objectives In this study …
Treatment strategies for cardiomyopathy in children: a scientific statement from the American Heart Association
C Bogle, SD Colan, SD Miyamoto, S Choudhry… - Circulation, 2023 - Am Heart Assoc
This scientific statement from the American Heart Association focuses on treatment
strategies and modalities for cardiomyopathy (heart muscle disease) in children and serves …
strategies and modalities for cardiomyopathy (heart muscle disease) in children and serves …
[HTML][HTML] Long-term effects of pediatric acute lymphoblastic leukemia chemotherapy: can recent findings inform old strategies?
ZN Al-Mahayri, MM AlAhmad, BR Ali - Frontiers in Oncology, 2021 - frontiersin.org
During the last few decades, pediatric acute lymphoblastic leukemia (ALL) cure rates have
improved significantly with rates exceeding 90%. Parallel to this remarkable improvement …
improved significantly with rates exceeding 90%. Parallel to this remarkable improvement …
[HTML][HTML] Cardioprotective strategies from cardiotoxicity in cancer patients: a comprehensive review
C Kourek, M Touloupaki, A Rempakos, K Loritis… - Journal of …, 2022 - mdpi.com
Cardiotoxicity is a significant complication of chemotherapeutic agents in cancer patients.
Cardiovascular incidents including LV dysfunction, heart failure (HF), severe arrhythmias …
Cardiovascular incidents including LV dysfunction, heart failure (HF), severe arrhythmias …
[HTML][HTML] Doxorubicin-induced acute cardiotoxicity is associated with increased oxidative stress, autophagy, and inflammation in a murine model
Drug-induced cardiotoxicity is a life-threatening side effect of doxorubicin (DOX) treatment
that impacts patient prognosis and survival. In the majority of cases, the acute clinical form …
that impacts patient prognosis and survival. In the majority of cases, the acute clinical form …
The role of mitochondrial quality control in anthracycline‐induced cardiotoxicity: from bench to bedside
Y Li, R Lin, X Peng, X Wang, X Liu, L Li… - Oxidative Medicine …, 2022 - Wiley Online Library
Cardiotoxicity is the major side effect of anthracyclines (doxorubicin, daunorubicin,
epirubicin, and idarubicin), though being the most commonly used chemotherapy drugs and …
epirubicin, and idarubicin), though being the most commonly used chemotherapy drugs and …
[HTML][HTML] Cardiovascular disease in adult cancer survivors: a review of current evidence, strategies for prevention and management, and future directions for cardio …
Abstract Purpose of Review Cardiovascular disease is long-term complication of both
cancer and anti-cancer treatment and can have significant ramifications for health-related …
cancer and anti-cancer treatment and can have significant ramifications for health-related …