Aims With improved diagnosis and treatments, a greater percentage of breast cancer
patients are achieving long-term survival. Consequently, long-term cardiotoxicity secondary …

Background Bone marrow transplantation (BMT) has significantly improved survival rates in
various hematological malignancies. However, this has led to an increased prevalence of …

Doxorubicin (DOXO) induces marked cardiotoxicity, though increased oxidative stress while
there are some documents related with cardioprotective effects of some antioxidants against …

BACKGROUND Doxorubicin and other anthracycline derivatives inhibit topoisomerase II
and is an important class of cytotoxic chemotherapy in cancer treatment. The use of …

Neuroblastoma (NB) is a pediatric malignancy that accounts for 15% of cancer-related
childhood mortality. High-risk NB requires an aggressive chemoradiotherapy regimen that …

Introduction Over the past five decades, the diagnosis and management of children with
various malignancies have improved tremendously. As a result, an increasing number of …

Background We aimed to compare the changes in blood metabolomes and cardiac
parameters following doxorubicin treatment in HER2-positive and HER2-negative breast …

Survivorship issues and treatment related toxicities have considerably increased in breast
cancer patients following improved therapeutic options. Cardiotoxicity has been a major …

Introduction Cardiovascular diseases are the main cause of treatment-related morbidity and
mortality in childhood cancer patients. Anthracyclines, one of the most common …

The quest of defeating cancer and improving prognosis in survivors has generated
remarkable strides forward in research and have advanced the development of new …