A troubled heart: Mood disorder history longitudinally predicts faster cardiopulmonary aging in breast cancer survivorship

AA Madison, M Filatov, R Andridge, G Haas… - Plos one, 2023 - journals.plos.org
Objective Breast cancer survivors live longer due to more advanced cancer treatments;
however, cardiovascular disease (CVD) is the leading non-cancer cause of death in breast …

An update of the molecular mechanisms underlying anthracycline induced cardiotoxicity

S Xie, Y Sun, X Zhao, Y Xiao, F Zhou, L Lin… - Frontiers in …, 2024 - frontiersin.org
Anthracycline drugs mainly include doxorubicin, epirubicin, pirarubicin, and aclamycin,
which are widely used to treat a variety of malignant tumors, such as breast cancer …

Initial Phase of Anthracycline Cardiotoxicity Involves Cardiac Fibroblasts Activation and Metabolic Switch

M Telesca, M Donniacuo, G Bellocchio, MA Riemma… - Cancers, 2023 - mdpi.com
Simple Summary One of the oldest anticancer drugs in use is doxorubicin. It associates with
cardiotoxicity that until now remains unresolved. Diastolic cardiac dysfunction can be the first …

[HTML][HTML] Anthracycline-induced cardiotoxicity in breast cancer patients: A five-year retrospective study in 10 centers

FR Gerodias Jr, MK Tan, A De Guzman… - Cardiology …, 2022 - ncbi.nlm.nih.gov
Background Cardiotoxicity as a result of anthracycline chemotherapy has been linked to
increased morbidity and mortality in breast cancer patients. There is a need for early …

A pilot study of associations between the occurrence of palpitations and cytokine gene variations in women prior to breast cancer surgery

Y Sheng, JS Carpenter, BJ Smith… - Biological Research …, 2023 - journals.sagepub.com
Objectives Palpitations are common and have a negative impact on women's quality of life.
While evidence suggests that inflammatory mechanisms may play a role in the development …

Approach to the Older Patient with Acute Myeloid Leukemia

M Zimmer, T Kadia - Current oncology reports, 2023 - Springer
Abstract Purpose of Review This study aims to review the challenges of treating AML in
older patients, the spectrum of genomic aberrancies in this cohort, and discuss treatment …

Kinetics and mechanism of synthesis of carboxyl-containing N-vinyl-2-pyrrolidone telehelics for pharmacological use

AN Kuskov, AL Luss, IA Gritskova, MI Shtilman… - Polymers, 2021 - mdpi.com
It was found that sulfanylethanoic and 3-sulfanylpropanoic acids are effective regulators of
molecular weight with chain transfer constants of 0.441 and 0.317, respectively, and show …

Dual integrin αvβ3 and αvβ5 blockade attenuates cardiac dysfunction by reducing fibrosis in a rat model of doxorubicin-induced cardiomyopathy

S Sui, Y Hou - Scandinavian Cardiovascular Journal, 2021 - Taylor & Francis
Objective: The present study aimed to evaluate the protective role of cilengitide (CGT), an
integrin αvβ3 and αvβ5 inhibitor, on doxorubicin (DOX)-induced myocardial fibrosis and …

Cardiovascular Disease in Women With Breast Cancer: A Contemporary Review

AP Barragán, PN Escobar, AM Miller… - International Journal of …, 2024 - SciELO Brasil
Breast cancer (BC) is the most common malignant neoplasia in women and is responsible
for one in six deaths from cancer in the female population. Five years after diagnosis, BC …

Circular RNAs: a small piece in the heart failure puzzle

R Eshraghi, D Shafie, A Raisi, P Goleij… - Functional & Integrative …, 2024 - Springer
Cardiovascular disease, specifically heart failure (HF), remains a significant concern in the
realm of healthcare, necessitating the development of new treatments and biomarkers. The …