The impact of the Fungus-Host-Microbiota interplay upon Candida albicans infections: current knowledge and new perspectives

C d'Enfert, AK Kaune, LR Alaban… - FEMS microbiology …, 2021 - academic.oup.com
Candida albicans is a major fungal pathogen of humans. It exists as a commensal in the oral
cavity, gut or genital tract of most individuals, constrained by the local microbiota, epithelial …

The Aspergillus fumigatus cell wall integrity signaling pathway: drug target, compensatory pathways, and virulence

V Valiante, J Macheleidt, M Föge… - Frontiers in …, 2015 - frontiersin.org
Aspergillus fumigatus is the most important airborne fungal pathogen, causing severe
infections with invasive growth in immunocompromised patients. The fungal cell wall (CW) …

Adhesion-dependent rupturing of Saccharomyces cerevisiae on biological antimicrobial nanostructured surfaces

K Nowlin, A Boseman, A Covell… - Journal of The …, 2015 - royalsocietypublishing.org
Recent studies have shown that some nanostructured surfaces (NSS), many of which are
derived from surfaces found on insect cuticles, rupture and kill adhered prokaryotic …

[HTML][HTML] Fungal model systems and the elucidation of pathogenicity determinants

E Perez-Nadales, MFA Nogueira, C Baldin… - Fungal genetics and …, 2014 - Elsevier
Fungi have the capacity to cause devastating diseases of both plants and animals, causing
significant harvest losses that threaten food security and human mycoses with high mortality …

Synthesis, characterization, molecular dynamic simulation, and biological assessment of cinnamates linked to imidazole/benzimidazole as a CYP51 inhibitor

AR Zala, DP Rajani, I Ahmad, H Patel… - Journal of Biomolecular …, 2023 - Taylor & Francis
Abstract A class of 2-(1 H-imidazol-1-yl)-1-phenylethyl cinnamates 6a-6j and 2-(1 H-benzo
[d] imidazol-1-yl)-1-phenylethyl cinnamates 7a-7j were synthesized, and their synthesis was …

Interference of Aspergillus fumigatus with the immune response

T Heinekamp, H Schmidt, K Lapp, V Pähtz… - Seminars in …, 2015 - Springer
Aspergillus fumigatus is a saprotrophic filamentous fungus and also the most prevalent
airborne fungal pathogen of humans. Depending on the host's immune status, the variety of …

Antifungal and cytotoxic activities of sixty commercially-available essential oils

CN Powers, JL Osier, RL McFeeters, CB Brazell… - Molecules, 2018 - mdpi.com
There is an urgent and unmet need for new antifungal therapies. Global fungal infection
rates continue to rise and fungal infections pose increasing burdens on global healthcare …

A review on computational systems biology of pathogen–host interactions

S Durmuş, T Çakır, A Özgür, R Guthke - Frontiers in microbiology, 2015 - frontiersin.org
Pathogens manipulate the cellular mechanisms of host organisms via pathogen–host
interactions (PHIs) in order to take advantage of the capabilities of host cells, leading to …

Computational systems biology in disease modeling and control, review and perspectives

R Yue, A Dutta - npj Systems Biology and Applications, 2022 - nature.com
Omics-based approaches have become increasingly influential in identifying disease
mechanisms and drug responses. Considering that diseases and drug responses are co …

Defining the transcriptomic landscape of Candida glabrata by RNA-Seq

J Linde, S Duggan, M Weber, F Horn… - Nucleic acids …, 2015 - academic.oup.com
Candida glabrata is the second most common pathogenic Candida species and has
emerged as a leading cause of nosocomial fungal infections. Its reduced susceptibility to …