Modern medicine has been waging a war on cancer for nearly a century with no tangible
end in sight. Cancer treatments have significantly progressed, but the need to increase …

Radiation therapy has been used worldwide for many decades as a therapeutic regimen for
the treatment of different types of cancer. Just over 50% of cancer patients are treated with …

With phenotypic heterogeneity in whole cell populations widely recognised, the demand for
quantitative and temporal analysis approaches to characterise single cell morphology and …

Purpose Pathologic complete response (pCR) is a critical factor in determining whether
patients with rectal cancer (RC) should have surgery after neoadjuvant chemoradiotherapy …

Chemotherapy is the most common clinical choice of treatment for cancer, however,
acquired chemoresistance is a major challenge that limits the successful outcome of this …

One of the key issues hampering the development of effective treatments for prostate cancer
is the lack of suitable, tractable, and patient-specific in vitro models that accurately …

Prostate cancer (PCa) arises from a cancer stem or progenitor cell with homogenous
characteristics, especially among the aging men population. Over the past decade, the …

Immune checkpoint inhibitors have become a promising new therapy for cancer treatment.
However, due to prostate cancer's high heterogeneity and immune-suppressive tumour …

The ability to distinguish malignant from indolent prostate cancer cells is critically important
for identification of clinically significant prostate cancer to minimize unnecessary …

Background/Aim: Interleukin 6 (IL6) is increased in patients with progressive prostate cancer
and induces its transdifferentiation to neuroendocrine prostate cancer. Neuroendocrine …