[HTML][HTML] The complex association of FcγRIIb with autoimmune susceptibility
JS Verbeek, S Hirose, H Nishimura - Frontiers in Immunology, 2019 - frontiersin.org
FcγRIIb is the only inhibitory Fc receptor and controls many aspects of immune and
inflammatory responses. The observation 19 years ago that FcγRIIb−/− mice generated by …
inflammatory responses. The observation 19 years ago that FcγRIIb−/− mice generated by …
Inhibitory B cell co-receptors and autoimmune diseases
T Tsubata - Immunological medicine, 2019 - Taylor & Francis
B cells express various inhibitory co-receptors including CD22 (also known as Siglec-2),
Siglec-10 (Siglec-G in mice), CD72, LILRB (PIR-B in mice) and FcγRIIB that contain …
Siglec-10 (Siglec-G in mice), CD72, LILRB (PIR-B in mice) and FcγRIIB that contain …
[HTML][HTML] The STING inhibitor (ISD-017) reduces glomerulonephritis in 129.B6.Fcgr2b-deficient mice
I Alee, P Chantawichitwong, A Leelahavanichkul… - Scientific Reports, 2024 - nature.com
The absence of stimulator of interferon genes (STING) in 129. B6. Fcgr2b-deficient mice
rescue lupus phenotypes. The administration of a STING inhibitor (ISD017) into the young …
rescue lupus phenotypes. The administration of a STING inhibitor (ISD017) into the young …
Gp49B is a pathogenic marker for auto-antibody-producing plasma cells in lupus-prone BXSB/Yaa mice
YL Wong, MT Su, A Sugahara-Tobinai… - International …, 2019 - academic.oup.com
AbstractImmune homeostasis is critically regulated by the balance between activating and
inhibitory receptors expressed on various immune cells such as T and B lymphocytes, and …
inhibitory receptors expressed on various immune cells such as T and B lymphocytes, and …
Distinct and synergistic roles of FcγRIIB deficiency and 129 strain-derived SLAM family proteins in the development of spontaneous germinal centers and …
C Soni, PP Domeier, EB Wong, TN Khan, MJ Elias… - Journal of …, 2015 - Elsevier
Abstract The inhibitory IgG Fc receptor (FcγRIIB) deficiency and 129 strain-derived signaling
lymphocyte activation molecules (129-SLAMs) are proposed to contribute to the lupus …
lymphocyte activation molecules (129-SLAMs) are proposed to contribute to the lupus …
The Unique Inhibitory IgG Receptor--FcγRIIb
Z Xu, L Liu, Z Cui, K Bi, N Zhang… - Protein and Peptide …, 2018 - ingentaconnect.com
Background: FcγRIIb is the only inhibitory IgG receptor, which is divided into three subtypes
of FcγRIIb1, FcγRIIb2 and FcγRIIb3. It is mainly responsible for the immune balance in vivo …
of FcγRIIb1, FcγRIIb2 and FcγRIIb3. It is mainly responsible for the immune balance in vivo …
FcγRIIb on B cells and myeloid cells modulates B cell activation and autoantibody responses via different but synergistic pathways in lupus-prone Yaa mice
Q Lin, M Ohtsuji, H Amano, H Tsurui… - The Journal of …, 2018 - journals.aai.org
Abstract C57BL/6 (B6). FcγRIIb−/−. Yaa mice spontaneously develop lethal lupus nephritis.
To define the cell type–specific role of FcγRIIb in Yaa-associated lupus, we established B …
To define the cell type–specific role of FcγRIIb in Yaa-associated lupus, we established B …
Fc Gamma Receptors and Phagocytosis in Immune Thrombocytopenia
PAA Norris - 2022 - search.proquest.com
Immune thrombocytopenia (ITP) is an autoimmune disease characterized by a low platelet
count in the absence of secondary or other explanations of thrombocytopenia. Platelet …
count in the absence of secondary or other explanations of thrombocytopenia. Platelet …
[PDF][PDF] Distinct and synergistic roles of FcgRIIB deficiency and 129 strain-derived SLAM family proteins in the development of spontaneous germinal centers and …
MJ Elias, SL Schell, AE Lukacher… - Journal of …, 2015 - researchgate.net
abstract The inhibitory IgG Fc receptor (FcgRIIB) deficiency and 129 strain-derived signaling
lymphocyte activation molecules (129-SLAMs) are proposed to contribute to the lupus …
lymphocyte activation molecules (129-SLAMs) are proposed to contribute to the lupus …
SLE 病原性B 細胞を特徴付ける抑制性受容体分子の探索
高井俊行， 乾匡範 - アレルギー, 2017 - jstage.jst.go.jp
全身性エリテマトーデス (SLE) は B リンパ球の抑制機構が破綻し, クロマチンや DNA
など細胞核内成分に反応する自己抗体 (抗核抗体, ANA) が病的レベルにまで増加し …
など細胞核内成分に反応する自己抗体 (抗核抗体, ANA) が病的レベルにまで増加し …