[HTML][HTML] Amphotericin B and other polyenes—Discovery, clinical use, mode of action and drug resistance

H Carolus, S Pierson, K Lagrou, P Van Dijck - Journal of Fungi, 2020 - mdpi.com
Although polyenes were the first broad spectrum antifungal drugs on the market, after 70
years they are still the gold standard to treat a variety of fungal infections. Polyenes such as …

Fungal evolution: major ecological adaptations and evolutionary transitions

MA Naranjo‐Ortiz, T Gabaldón - Biological Reviews, 2019 - Wiley Online Library
Fungi are a highly diverse group of heterotrophic eukaryotes characterized by the absence
of phagotrophy and the presence of a chitinous cell wall. While unicellular fungi are far from …

Identification of molds by matrix-assisted laser desorption ionization–time of flight mass spectrometry

M Sanguinetti, B Posteraro - Journal of Clinical Microbiology, 2017 - Am Soc Microbiol
Although to a lesser extent than diagnostic bacteriology, matrix-assisted laser desorption
ionization–time of flight mass spectrometry (MALDI-TOF MS) has recently revolutionized the …

Zinc and manganese chelation by neutrophil S100A8/A9 (calprotectin) limits extracellular Aspergillus fumigatus hyphal growth and corneal infection

HL Clark, A Jhingran, Y Sun, C Vareechon… - The Journal of …, 2016 - journals.aai.org
Calprotectin, a heterodimer of S100A8 and S100A9, is an abundant neutrophil protein that
possesses antimicrobial activity primarily because of its ability to chelate zinc and …

Current antifungal treatment of fusariosis

AMS Al-Hatmi, A Bonifaz, S Ranque… - International Journal of …, 2018 - Elsevier
Fungi of the genus Fusarium are well known as major plant pathogens and soil inhabitants,
but also cause a broad spectrum of human infections. Fusariosis is the second most …

[HTML][HTML] Antimicrobial and antioxidant properties of medicinal plants used by the Bentian tribe from Indonesia

IW Kusuma, ET Arung, Y Kim - Food Science and Human Wellness, 2014 - Elsevier
Some selected medicinal plants used by Bentian tribe from Indonesia were evaluated for
potential antimicrobial and antioxidant properties. The leaves stem bark and root of the …

[HTML][HTML] Bench-to-bedside review: Rapid molecular diagnostics for bloodstream infection-a new frontier?

A Afshari, J Schrenzel, M Ieven, S Harbarth - Critical care, 2012 - Springer
Among critically ill patients, the diagnosis of bloodstream infection poses a major challenge.
Current standard bacterial identification based on blood culture platforms is intrinsically time …

Isavuconazole, micafungin, and 8 comparator antifungal agents' susceptibility profiles for common and uncommon opportunistic fungi collected in 2013: temporal …

MA Pfaller, PR Rhomberg, SA Messer… - … and infectious disease, 2015 - Elsevier
The in vitro activities of isavuconazole, micafungin, and 8 comparator antifungal agents were
determined for 1613 clinical isolates of fungi (1320 isolates of Candida spp., 155 of …

Impact of COVID-19 on the antifungal susceptibility profiles of isolates collected in a global surveillance program that monitors invasive fungal infections

MA Pfaller, CG Carvalhaes, S DeVries… - Medical …, 2022 - academic.oup.com
Studies demonstrated the impact of the COVID-19 pandemic in the prevalence and
susceptibility profiles of bacterial and fungal organisms. We analyzed 4821 invasive fungal …

In Vitro and In Vivo Activities of Pterostilbene against Candida albicans Biofilms

DD Li, LX Zhao, E Mylonakis, GH Hu… - Antimicrobial Agents …, 2014 - Am Soc Microbiol
Pterostilbene (PTE) is a stilbene-derived phytoalexin that originates from several natural
plant sources. In this study, we evaluated the activity of PTE against Candida albicans …