[HTML][HTML] Recommended treatment for antibody-mediated rejection after kidney transplantation: the 2019 expert consensus from the transplantion society working …

CA Schinstock, RB Mannon, K Budde, AS Chong… - …, 2020 - journals.lww.com
This meeting was organized by The Transplantation Society with the assistance of an
unconditional education grant from CSL Behring. CSL Behring had no involvement in the …

Precision transplant medicine: biomarkers to the rescue

M Naesens, D Anglicheau - Journal of the American Society of …, 2018 - journals.lww.com
The concept that individuals with the same disease and a similar clinical presentation may
have very different outcomes and need very different therapies is not novel. With the …

Prediction system for risk of allograft loss in patients receiving kidney transplants: international derivation and validation study

A Loupy, O Aubert, BJ Orandi, M Naesens, Y Bouatou… - Bmj, 2019 - bmj.com
Objective To develop and validate an integrative system to predict long term kidney allograft
failure. Design International cohort study. Setting Three cohorts including kidney transplant …

[HTML][HTML] Attention2majority: Weak multiple instance learning for regenerative kidney grading on whole slide images

Z Su, TE Tavolara, G Carreno-Galeano, SJ Lee… - Medical Image …, 2022 - Elsevier
Deep learning consistently demonstrates high performance in classifying and segmenting
medical images like CT, PET, and MRI. However, compared to these kinds of images, whole …

Development and validation of a peripheral blood mRNA assay for the assessment of antibody-mediated kidney allograft rejection: a multicentre, prospective study

E Van Loon, S Gazut, S Yazdani, E Lerut, H de Loor… - …, 2019 - thelancet.com
Background Antibody-mediated rejection, a leading cause of renal allograft graft failure, is
diagnosed by histological assessment of invasive allograft biopsies. Accurate non-invasive …

[HTML][HTML] Surrogate endpoints for late kidney transplantation failure

M Naesens, K Budde, L Hilbrands… - Transplant …, 2022 - frontierspartnerships.org
In kidney transplant recipients, late graft failure is often multifactorial. In addition, primary
endpoints in kidney transplantation studies seek to demonstrate the short-term efficacy and …

Data-driven chronic allograft phenotypes: a novel and validated complement for histologic assessment of kidney transplant biopsies

T Vaulet, G Divard, O Thaunat, P Koshy… - Journal of the …, 2022 - journals.lww.com
Background No validated system currently exists to realistically characterize the chronic
pathology of kidney transplants that represents the dynamic disease process and spectrum …

[HTML][HTML] Challenges in the management of the kidney allograft: from decline to failure: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) …

MA Josephson, Y Becker, K Budde, BL Kasiske… - Kidney international, 2023 - Elsevier
In March 2022, Kidney Disease: Improving Global Outcomes (KDIGO) held a virtual
Controversies Conference to address the important but rarely examined phase during which …

Prognostic biomarkers in kidney transplantation: a systematic review and critical appraisal

M Raynaud, S Al-Awadhi, K Louis… - Journal of the …, 2024 - journals.lww.com
Background Despite the increasing number of biomarker studies published in the transplant
literature over the past 20 years, demonstrations of their clinical benefit and their …

Chronic allograft injury

E Langewisch, RB Mannon - … Journal of the American Society of …, 2021 - journals.lww.com
With the incremental improvements in long-term kidney transplant survival, there is renewed
focus on what causes failure of the transplanted allograft. Over the past decade, our …