Flavonoids and their biological secrets

MI Rashid, MI Fareed, H Rashid, H Aziz… - Plant and Human Health …, 2019 - Springer
Flavonoids are tricyclic polyphenolic compounds naturally occurring in plants. Being
nature's antioxidants flavonoids have been shown to reduce the damages induced by …

[HTML][HTML] Anti-tumor effect of α-pinene on human hepatoma cell lines through inducing G2/M cell cycle arrest

W Chen, Y Liu, M Li, J Mao, L Zhang, R Huang… - Journal of …, 2015 - Elsevier
Abstracts Pine needle oil from crude extract of pine needles has been used as an anti-
cancer agent in Traditional Chinese Medicine. The α-pinene is a natural compound isolated …

DNA damage response and repair in the development and treatment of brain tumors

PM Dana, F Sadoughi, H Mirzaei, Z Asemi… - European Journal of …, 2022 - Elsevier
DNA damage response (DDR) comprising DNA repair and cell-cycle checkpoint pathways,
is considered as a protective process that maintains the integrity of the genome. However …

[HTML][HTML] Endometrial mesenchymal stem cells isolated from menstrual blood repaired epirubicin-induced damage to human ovarian granulosa cells by inhibiting the …

Z Yan, F Guo, Q Yuan, Y Shao, Y Zhang… - Stem Cell Research & …, 2019 - Springer
Background To explore the effect of mesenchymal stem cells isolated from menstrual blood
(MB-MSCs) on epirubicin-induced damage to human ovarian granulosa cells (GCs) and its …

Gossypin inhibits gastric cancer growth by direct targeting of AURKA and RSK2

L Wang, X Wang, H Chen, X Zu, F Ma… - Phytotherapy …, 2019 - Wiley Online Library
Gossypin is a flavone extracted from Hibiscus vitifolius, which has been reported to exhibit
anti‐inflammatory, antioxidant, and anticancer activities. However, the anticancer properties …

Gossypin: a flavonoid with diverse pharmacological effects

B Song, X Shen, C Tong, S Zhang… - Chemical Biology & …, 2023 - Wiley Online Library
Gossypin is a flavonoid compound prepared from chinese medicine Hibiscus, which not only
has significant pharmacological activities in antioxidant, anti‐inflammatory, neuroprotective …

[HTML][HTML] Therapeutic benefits of gossypin as an emerging phytoconstituents of Hibiscus spp.: a critical review

G Jejurkar, M Chavan - Future Journal of Pharmaceutical Sciences, 2023 - Springer
Background Flavonoids are one of the crucial secondary metabolites as several functions
are carried out by flavonoids, including regulating cell growth, luring insects and pollinators …

[HTML][HTML] Diallyl disulfide selectively causes checkpoint kinase-1 mediated G2/M arrest in human MGC803 gastric cancer cell line

H Ling, LF Lu, J He, GH Xiao, H Jiang… - Oncology …, 2014 - spandidos-publications.com
Previous studies have shown that diallyl disulfide (DADS), a naturally occurring anticancer
agent in garlic, arrested human gastric cancer cells (MGC803) in the G2/M phase of the cell …

Anticancer Effects and Molecular Mechanisms of Gossypin on Phosphatidylinositol 3-Kinase/Protein Kinase B Inhibition in Human Nonsmall Cell Lung Cancer Cell …

SU Lee, YH Kim - Natural Product Communications, 2023 - journals.sagepub.com
Nonsmall cell lung cancer (NSCLC) accounts for approximately 80%–85% of all lung cancer
patients. Gossypin, a flavonoid contained in Hibiscus vitifolius, has been reported as a …

Demethoxycurcumin was prior to temozolomide on inhibiting proliferation and induced apoptosis of glioblastoma stem cells

L Shi, X Fei, Z Wang - Tumor Biology, 2015 - Springer
Temozolomide (TMZ) is widely used for treating glioblastoma (GBM), which can effectively
inhibit the GBM growth for some months; however, it still could not prevent the invariable …